| 莫西沙星与阿奇霉素联合头孢哌酮/舒巴坦治疗社区获得性肺炎的疗效观察 |
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| 引用本文： | 刘丽莹,肖永濠,严鹏科,许俊,关秉恩. 莫西沙星与阿奇霉素联合头孢哌酮/舒巴坦治疗社区获得性肺炎的疗效观察[J]. 中国医院用药评价与分析, 2012, 0(6): 543-545 |
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| 作者姓名： | 刘丽莹 肖永濠 严鹏科 许俊 关秉恩 |
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| 作者单位： | 广州医学院第三附属医院药剂科;广州市海珠区妇幼保健院药剂科 |
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| 摘 要： | 目的:观察莫西沙星与抗菌谱相近的阿奇霉素联合头孢哌酮/舒巴坦治疗社区获得性肺炎的临床疗效和安全性。方法:收集66例社区获得性肺炎患者,以随机抽样法分为2组。实验组(33例)给予莫西沙星注射液0.4 g,qd,静脉滴注;对照组(33例)给予阿奇霉素0.5 g,qd,联合头孢哌酮/舒巴坦2.5 g,bid,静脉滴注。结果:疗程结束后,2组在临床疗效、细菌清除率、不良反应方面比较,差异均无统计学意义(P>0.05)。结论:莫西沙星治疗社区获得性肺炎疗效确切,安全性与阿奇霉素联合头孢哌酮/舒巴坦相似。
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| 关 键 词： | 莫西沙星 阿奇霉素 头孢哌酮舒巴坦 社区获得性肺炎 |
Efficacy of Moxifloxacin vs. Azithromycin Plus Cefoperazone/Sulbactam for Community Acquired Pneumonia |
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| LIU Li-ying,XIAO Yong-hao,YAN Peng-ke,XU Jun,GUAN Bing-en. Efficacy of Moxifloxacin vs. Azithromycin Plus Cefoperazone/Sulbactam for Community Acquired Pneumonia[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2012, 0(6): 543-545 |
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| Authors: | LIU Li-ying XIAO Yong-hao YAN Peng-ke XU Jun GUAN Bing-en |
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| Affiliation: | 1(1.Dept.of Pharmacy,The Third Affiliated Hospital of Guangzhou Medical College,Guangzhou 510150,China;2.Dept.of Pharmacy,Guangzhou Haizhu District Maternal and Child Care Service Center,Guangzhou 510240,China) |
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| Abstract: | OBJECTIVE: To evaluate the clinical efficacy and safety of moxifloxacin versus azithromycin(of similar antimicrobial spectrum) plus cefoperazone/sulbactam in the treatment of community acquired pneumonia.METHODS: 66 patients with community acquired pneumonia were randomized divided into 2 groups,of 33 each.The trial group received moxifloxacin(0.4 g,q.d) by iv gtt and the control group received azithromycin(0.5 g,q.d) plus cefoperazone/sulbactam(2.5 g,bid) by iv gtt.RESULTS: After treatment completion,there were no statistical differences between the two groups in respect of therapeutic effect,bacterium clearance rate and adverse drug reactions(P>0.05).CONCLUSION: Moxifloxacin is proved to be effective and as safe as azithromycin plus cefoperazone/sulbactam in the treatment of community acquired pneumonia. |
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| Keywords: | Moxifloxacin Azithromycin Cefoperazone/sulbactam Community acquired pneumonia |
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