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Increased prevalence of cavum septum pellucidum in schizophrenia |
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| Authors: | M.D.Lynn E. DeLisi Associate Professor of Psychiatry Ph.D.Anne L. Hoff Research Director M.S.W.Maureen Kushner Research Social Worker Project Coordinator M.D.Gustav Degreef formerly Clinical Director of Magnetic Resonance Imaging Studies |
| Affiliation: | aDepartment of Psychiatry and Behavioral Science, School of Medicine, State University of New York at Stony Brook, USA bBiological Psychiatry Treatment and Research Center, Napa State Hospital, California, USA cPsychiatry Research Department, Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, NY, USA |
| Abstract: | A previous report that the presence of a cavum septum pellucidum was significantly more common in schizophrenic patients than in control subjects (DeGreef et al., 1992) stimulated the present study of an independent but similar population of first admission schizophrenic patients. A high prevalence of this developmental anomaly (44.8%) was found in the patients (n = 85), although it could also be detected in 29.8% of similarly aged control subjects (n = 47). This finding was not associated with corpus callosum, ventricular, or temporal lobe size or asymmetries. |
| Keywords: | Magnetic resonance imaging schizophreniform psychosis brain developmental anomalies |
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