Global serotype distribution among Streptococcus pneumoniae isolates causing otitis media in children: Potential implications for pneumococcal conjugate vaccines |
| |
| Authors: | Gail L. Rodgers Adriano Arguedas Robert Cohen Ron Dagan |
| |
| Affiliation: | 1. Scientific Affairs and Global Medical Affairs, Vaccines, Wyeth Pharmaceuticals Inc., 500 Arcola Road, Collegeville, PA 19426, USA;2. Instituto de Atención Pediátrica, Universidad de Ciencias Médicas, San José, Costa Rica;3. ACTIV, Department of Microbiology, Centre Hospitalier Intercommunal de Créteil, Créteil, France;4. Pediatric Infectious Disease Unit, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel |
| |
| Abstract: | Acute otitis media (AOM) is the most common infection following pneumococcal colonization of the upper respiratory tract. Streptococcus pneumoniae causes 30–60% of AOM cases worldwide. However, not all pneumococcal serotypes cause disease and an association exists with nasopharyngeal colonization by certain serotypes and their propensity to cause AOM. This review examines the global serotype distribution relationship between pneumococcal serotypes and AOM in children aged <18 years and demonstrates that the most common pneumococcal serotypes causing AOM globally are 3, 6A, 6B, 9V, 14, 19A, 19F, and 23F. |
| |
| Keywords: | Streptococcus pneumoniae Otitis media Serotype |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
