| 丁丙诺啡治疗海洛因依赖戒断综合征临床疗效分析 |
| |
| 引用本文： | 刘海波,;商田歌. 丁丙诺啡治疗海洛因依赖戒断综合征临床疗效分析[J]. 临床心身疾病杂志, 2014, 0(4): 111-112 |
| |
| 作者姓名： | 刘海波, 商田歌 |
| |
| 作者单位： | [1]肇庆市第一人民医院,广东肇庆526040; [2]肇庆市端州区红十字会医院,广东肇庆526040 |
| |
| 摘 要： | 目的：探讨丁丙诺啡治疗海洛因依赖戒断综合征的临床疗效。方法将521例海洛因依赖戒断综合征患者随机分为两组,研究组舌下含服丁丙诺啡,静脉滴注氟哌啶醇＋东莨菪碱治疗,对照组口服美沙酮治疗,观察2周。对两组临床疗效进行对比分析。结果研究组有效率为95．1％,对照组为75．1％,研究组有效率显著高于对照组（χ^2＝41．99,P＜0．01）。结论舌下含服丁丙诺啡、静脉滴注氟哌啶醇＋东莨菪碱治疗海洛因依赖戒断综合征疗效显著,优于美沙酮替代治疗。
|
| 关 键 词： | 海洛因依赖戒断综合征 丁丙诺啡 美沙酮 替代治疗 氟哌丁醇 东莨菪碱 |
The efficacy of buprenorphine in heroin dependence withdrawal syndrome |
| |
| Affiliation: | Liu Haibo, Shang Tiange(The First People＇s Hospital of Zhaoqing City, Zhaoqing 526040, Guangdong, China) |
| |
| Abstract: | Objective To explore the efficacy of buprenorphine in heroin dependence withdrawal syndrome （HDWS） .Methods A total of 521 HDWS patients were randomly assigned to two groups ,research group was treated with sublingually buccal buprenorphine and intravenous drip of haloperidol＋scopolamine ,and control group took orally methadone for 2 weeks .Efficacies of two groups were contrastively analyzed .Results Effective rate was respectively 95 .1% in research and 75 .1% in control group ,the former significantly higher than the latter （χ^2 =41 .99 ,P〈0 .01） .Conclusion Sublingually buccal buprenorphine and intravenous drip of haloperidol ＋ scopolamine have an evident effect compared with methadone replacement therapy in HAWS . |
| |
| Keywords: | HDWS buprenorphine methadone replacement therapy haloperidol scopolamine |
| 本文献已被 维普 等数据库收录！ |
|
