Epidermodysplasia verruciformis

Epidermodysplasia verrucif ormis (EV) is a rare, lifelong disease induced by a diversity of specific human papillomaviruses (HPVs) including, in some instances, the HPVs which induce plane warts in the general population.^1–4 EV provides a model of cutaneous viral oncogenesis, in which virus and host factors are important determinants.

The disease starts usually in early childhood. The lesions, as a rule, do not appear at birth, even in familial cases, in spite of the heavy viral infection of the mother. The reason for this latency period is not known.