| 铋剂联合三种抗生素清除幽门螺杆菌的临床研究 |
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| 引用本文： | 焦连华,刘伟,侯鹏飞,张锦春,杜秋菊,马军.铋剂联合三种抗生素清除幽门螺杆菌的临床研究[J].中国现代医生,2011,49(7):94-95. |
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| 作者姓名： | 焦连华 刘伟 侯鹏飞 张锦春 杜秋菊 马军 |
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| 作者单位： | 1. 濮阳市油田总医院消化内科,河南濮阳,457001
2. 郑州大学二附院消化内科,河南郑州,450003 |
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| 摘 要： | 目的了解同时三种抗生素联合应用铋剂清除幽门螺杆菌的有效性。方法将188例上消化道溃疡伴幽门螺杆菌感染的患者随机分为标三联和标三联基础上加用铋剂联合应用阿莫西林两组，治疗停止后4周复检Hp，两种方法均以Hp阴性为根除。结果联合用药组和标三联组Hp根除率分别为91．67％（88／96）和70．65％（65／92）；联合用药组Hp根除率显著高于标三联组（x2=16．96，P〈0．01），不良反应率无显著差异，服药依从性好。结论联合用药可显著提高幽门螺杆菌的根除率，该方法副作用小、依从性好，适合临床推广。
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| 关 键 词： | 幽门螺杆菌 铋剂 抗生素 |
The Clinical Study of Bismuth Combined with Three Kinds of Antibiotic for Helicobacter pylori Infection |
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| Authors: | JIAO Lianhua LIU Wei HOU Pengfei ZHANG Jinchun DU Qiuju MA Jun |
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| Institution: | JIAO Lianhua1 LIU Wei1 HOU Pengfei1 ZHANG Jinchun1 DU Qiuju1 MA Jun2 1.Department of Gastroenterology,the Central Hospital of Puyang Oil Field,Puyang 457001,China,2.Department of Gastroenterology,the Second Affiliated Hospital,Zhengzhou University,Zhengzhou 450003 |
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| Abstract: | Objective To study the clinical effects of Bismuth Combined with Three Kinds of Antibiotic for Helicobacter pylori Infection.Methods There were 188 patients with H.pylori infection were randomly divided into two groups,gave separately treatments for H.pylori eradication.After four weeks,to exam Hp again,and to observe the eradicative results.Results The management of Helicobacter pylori infection with three kinds of antibiotic was more effective91.67 vs 70.65 respectively with a significant difference(P<0.... |
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| Keywords: | Helicobacter pylori Bismuth Antibiotics |
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