首页 | 本学科首页   官方微博 | 高级检索  
     

白头翁诱导胃癌细胞凋亡的研究
引用本文:冯秀芝,刘伟,刘建平,陈锐,丁年良. 白头翁诱导胃癌细胞凋亡的研究[J]. 中国现代医生, 2011, 49(9): 1-2
作者姓名:冯秀芝  刘伟  刘建平  陈锐  丁年良
作者单位:宁波市保黎医院内科,浙江宁波,215031
摘    要:
目的研究中药白头翁对诱导胃癌BGC823细胞株凋亡过程的影响作用,探讨白头翁抗肿瘤的可能机制。方法以体外培养的胃癌BGC823细胞株为研究对象,MTI'法检测不同浓度白头翁对BGC823细胞活性的影响,采用流式细胞术检测不同浓度白头翁作用胃癌BGC823细胞24h后细胞凋亡率。结果白头翁对BGC823细胞活性的抑制呈浓度依赖性,白头翁抑制BGC823细胞增殖可能由于其诱导胃癌细胞凋亡所致。结论白头翁能诱导胃癌BGC823细胞株发生细胞凋亡,有望成为胃癌的辅助治疗药物。

关 键 词:白头翁  BGC823细胞株  细胞凋亡

Study of Apoptosis in Gastric Cancer Cells Induced by Chinese Pulsatilla Root
FENG Xiuzhi,LIU Wei,LIU Jianping,CHEN Rui,DING Nianliang. Study of Apoptosis in Gastric Cancer Cells Induced by Chinese Pulsatilla Root[J]. , 2011, 49(9): 1-2
Authors:FENG Xiuzhi  LIU Wei  LIU Jianping  CHEN Rui  DING Nianliang
Affiliation:FENG Xiuzhi LIU Wei LIU Jianping CHEN Rui DING Nianliang Internal Medicine Department,Baoli Hospital of Ningbo,Ningbo 215031,China
Abstract:
Objective To study the influence on apoptosis in gastric cancer cell lines BGC823 induced by Chinese Pulsatilla root,and explore the possible mechanism of antitumor in Pulsatilla.Methods Take the gastric cancer BGC823 cell in vitro as the study object,the active of BGC823 cell with different concentrations of Pulsatilla is examined by MTT assay,and BGC823 cell apoptosis examined by flow cytometry while different concentrations of Pulsatilla after BGC823 cell was processed 24 hours.Results The active of BGC8...
Keywords:Chinese pulsatilla root  BGC823 cell  Apoptosis  
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号