修正酸碱失衡预计代偿公式的初步研究

目的编制更为合理的单纯性酸碱失衡预计代偿范围计算公式。方法采纳Hamm公式的最大代偿系数及周寿生公式的代偿范围,编制成修正代偿公式。结果修正酸碱失衡预计代偿公式（修正公式）有A、B两种表达式,其最后计算结果完全一致,A表达式：代谢性酸中毒：PaCO2=40-1.4×△[HCO3-]↓＋（0-5）;代谢性碱中毒：PaCO2=40＋0.9×△[HCO3-]↑-（0-5）;急性呼吸性酸中毒：[HCO3-]=24＋0.175×△PaCO2↑-（0-3）;慢性呼吸性酸中毒：[HCO3-]=24＋0.55×△PaCO2↑-（0-3）;急性呼吸性碱中毒：[HCO3-]=24-0.25×△PaCO2↓＋（0-3）;慢性呼吸性碱中毒：[HCO3-]=24-0.5×△PaCO2↓＋（0-3）。B表达式与周寿生公式形式类似（略）。结论修正公式推理成立,无过度代偿,可减少双重性失衡的误判或漏判,且应用方便。

A Study of Expected Compensation Formulae for Acid-base Disorders

Objective To compile more reasonable compensation formulae for simple acid-base disorder.Methods The compensation coefficients of Hamm＇s formulae and the compensation ranges of Zhou＇s were adopted to compile modified compensation formulae for acid,base disorder.Results There were two kinds of expressions with the same the final calculated results.Expression A： metabolic acidosis： PaCO2=40-1.4×△↓＋（0～5）;metabolic alkalosis： PaCO2=40＋0.9×△↑-（0～5）;acute respiratory acidosis： [=24＋0.175×△PaCO2↑-（0～3）;chronic respiratory acidosis： =24＋0.55×△PaCO2↑-（0～3）;acute respiratory alkalosis： =24-0.25×△PaCO2↓＋（0～3）;chronic respiratory alkalosis： =24-0.5×△PaCO2↓＋（0～3）.Expression B was similar to that of Zhou＇s（expression omitted）.Conclusion The modified compensation formulae is reasonable,and can be used conveniently.There is no over-compensation,and misjudgement can be avoided.