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RAS/MAPK pathway hyperactivation determines poor prognosis in undifferentiated pleomorphic sarcomas
Authors:Javier Hernández‐Losa PhD  Sara Simonetti MD  Claudia Valverde MD  Teresa Moliné BS  Rosa Somoza BS  Manuel Pérez MD  Roberto Vélez MD  PhD  Ramona Vergés MD  PhD  Rosa Domínguez MD  Joan Carles MD  PhD  Santiago Ramón y Cajal MD  PhD
Affiliation:1. Department of Pathology, Vall d'Hebron University Hospital, Barcelona, Spain;2. Department of Medical Oncology, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain;3. Department of Orthopedic Surgery, Vall d'Hebron University Hospital, Barcelona, Spain;4. Department of Radiotherapy, Vall d'Hebron University Hospital, Barcelona, Spain;5. Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain
Abstract:
Keywords:KRAS  outcomes  phosphoinositide 3‐kinase inhibitor (PI3K)/mammalian target of rapamycin (mTOR) pathway  RAS/mitogen‐activated protein kinases (MAPK) pathway  undifferentiated pleomorphic sarcoma
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