人工皮肤体外培养

人工皮肤是指应用组织工程技术将体外培养的上皮细胞和成纤维细胞扩增后，接种于一种具有良好生物相容性的材料上，经体外培养，形成的皮肤。将其移植于皮肤创面处，可以实现创伤的修复和重建。本文分别从上皮体外培养，真皮体外培养及人工皮肤模型的建立、培养方法及其影响因素等方面对近年来人工皮肤的研究进展进行了综述。

Artificial Skin Cultured In Vitro

Artificial skin is a kind of skin which by using tissue engineering techniques, a skin-like material was formed by seeding epithelium cells and dermis fibroblasts on a good biocompatible material after proliferation.The trauma restoration and reconstruction were achieved by transplanting the skin graft an skin defects after the artificial skin graft cultured in vitro. Artificial skin research is a new active field in tissue engineering. It has wonderful prospect for clinics to radically settle the problem of restoration of skin defects. The recent studies on the models, cultured methods and influenced factors for epithium culture, dermis culture and artificial skin in vitro were reviewed in this paper.