肿瘤患者合并深静脉血栓的临床分析

目的:探讨恶性肿瘤并发血栓性疾病的危险因素,为及早预防提供依据.方法:收集30例恶性肿瘤并发血栓栓塞患者为病例组,并收集同期不伴有血栓栓塞的38例恶性肿瘤患者为对照组,回顾性分析恶性肿瘤并发血栓栓塞的危险因素.结果:病例组30例患者中,下肢深静脉血栓形成者24例,上肢深静脉血栓5例,肺栓塞者1例.观察组红细胞计数和血红蛋白值均低于对照组,血小板计数和D-二聚体高于对照组,差异均有统计学意义(P<0.05).恶性肿瘤并发血栓性疾病的发生在并发感染、接受手术、地塞米松治疗和中心静脉置管上存在差异(P<0.05).30例患者在肿瘤确诊2个月内并发血栓性疾病.结论:恶性肿瘤并发感染、地塞米松的应用、接受手术和中心静脉置管的应用时易并发血栓形成.

Clinical analysis ofcancerpatients withdeep veinthrombosis

Objective:To investigate the risk factors of cancer complicated by thrombotic disease. Methods:30 cancer patients with thromboembolism as case group,and 38 patients with malignant tumors without associated with thromboembolism as control group. Results:In 30 patients of case group,upper limbdeep venous thrombosis developed in 24 cases,five cases with lower limb deep vein thrombosis,pulmonary embolism in 1 case. Red blood cell countand hemoglobin observation group were lower than the control group,platelet count,and D-dimer higher,the difference-was statistically significant(P<0. 05). Malignant disease complicated by thrombosis occured in concurrent infections, surgery,there was differences(P<0. 05)in the treatment ofcentral venous catheter and dexamethasone. Conclusion:Cancer patients complicated with infection,dexamethasone surgery were easy to develop central venous thromboembo-lism.