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| 代谢组学技术在电离辐射防护研究中的应用 | |
| 引用本文： | 于纯淼,于苗苗,付佳琪,国立东,连莲,于栋华. 代谢组学技术在电离辐射防护研究中的应用[J]. 中国辐射卫生, 2022, 31(1): 129-134. DOI: 10.13491/j.issn.1004-714X.2022.01.023 |
| 作者姓名： | 于纯淼 于苗苗 付佳琪 国立东 连莲 于栋华 |
| 作者单位： | 黑龙江中医药大学，黑龙江 哈尔滨 150040 |
| 基金项目： | 国家自然科学基金（青年）（81803871）；黑龙江省博士后科研启动金资助项目（LBH-Q19186） |
| 摘 要： | 代谢组学作为系统生物学研究的重要方法,不仅在生命科学研究中发挥重要作用,在辐射防护研究领域的应用也日益广泛。本文从啮齿类动物、灵长类动物模型的代谢组学和代谢组学方法的临床研究等方面,综述代谢组学方法和技术在辐射损伤中的诊断和机制研究,以及在辐射防护药物研究中的价值。 |
| 关 键 词： | 代谢组学 电离辐射 辐射防护 |
| 收稿时间： | 2021-08-23 |
Application of metabolomics technology in the study of ionizing radiation protection |
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| YU Chunmiao,YU Miaomiao,FU Jiaqi,GUO Lidong,LIAN Lian,YU Donghua. Application of metabolomics technology in the study of ionizing radiation protection[J]. Chinese Journal of Radiological Health, 2022, 31(1): 129-134. DOI: 10.13491/j.issn.1004-714X.2022.01.023 | |
| Authors: | YU Chunmiao YU Miaomiao FU Jiaqi GUO Lidong LIAN Lian YU Donghua |
| Affiliation: | Heilongjiang University of Chinese Medicine, Harbin 150040 China |
| Abstract: | As an important method of systems biology, metabolomics not only plays an important role in life science but also has been increasingly widely used in radiation protection research. Based on the clinical studies of metabolomics and metabolomics methods in rodent and primate models, this article summarizes the methods and techniques of metabolomics in the diagnosis of radiation damage, the study of radiation damage mechanisms, and the development of radiation protection drugs. |
| Keywords: | Metabolomics Ionizing radiation Radiation protection |
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