胃癌术后全胃肠外营养治疗中患者出现低血糖的影响因素研究

目的 探讨胃癌术后患者在全胃肠外营养治疗期间出现低血糖的相关因素,为在临床治疗中降低患者低血糖发生率、为医护人员制定有效的预防和干预措施提供理论依据.方法 依托临床电子病历系统,采用回顾性研究的方法,收集2018年1月1日-2019年12月31日在中国科学院大学附属肿瘤医院腹部外科行胃癌根治手术的974例患者信息,按照...

Influencing factors of hypoglycaemia in post-operative total parenteral nutrition therapy for gastric cancer

  Objective  To explore the related factors of hypoglycaemia in patients with gastric cancer during total parenteral nutrition therapy and to provide a theoretical basis for reducing the incidence of hypoglycaemia in clinical treatment and for medical staff to formulate effective prevention and intervention measures.  Methods  A retrospective study was used to collect information on 974 patients who underwent radical gastric cancer surgery in the Department of Abdominal Surgery of the Tumor Hospital of the University of Chinese Academy of Sciences from January 1, 2018 to December 31, 2019. According to whether or not hypoglycaemia occurred, they were divided into hypoglycaemia group and non-hypoglycaemia group. The hypoglycaemia group was the observation group (126 cases), and the non-hypoglycaemia group was the control group (848 cases). The two groups compared their age, gender, past history, BMI, surgical methods, medication status and biochemical indicators. Univariate analysis was performed using t test and χ2 test. Multivariate analysis adopted binary logistic regression analysis.  Results  A total of 974 patients were enrolled in this study, including 660 males (67.8%) and 314 females (32.2%), with an average age of (61.2±10.5) years. A total of 126 cases of hypoglycaemia were reported, with an incidence of 12.9%. Binary logistic regression analysis showed that gender, BMI, previous diabetes history, insulin and glucose ratio were related to the occurrence of hypoglycaemia during total parenteral nutrition therapy in patients after gastric cancer surgery.  Conclusion  In nursing care, attention should be paid to high-risk groups, and targeted measures should be taken to improve the nutritional status of patients, use drugs safely and rationally, reduce post-operative stress and fasting time and reduce the incidence of hypoglycaemia.