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干性年龄相关性黄斑变性发病机制及治疗
引用本文:张敬法,张宇萌,孙晓东. 干性年龄相关性黄斑变性发病机制及治疗[J]. 眼科新进展, 2022, 0(3): 169-178. DOI: 10.13389/j.cnki.rao.2022.0035
作者姓名:张敬法  张宇萌  孙晓东
作者单位:200080 上海市第一人民医院眼科
摘    要:
目前,干性年龄相关性黄斑变性尚无有效的治疗方法,但近年的临床试验显示出巨大的治疗前景,包括饮食疗法、抗体疗法、基因治疗、细胞治疗和激光治疗等.本文就干性年龄相关性黄斑变性的病理特征、发病机制和治疗方法等进行述评,以期为干性年龄相关性黄斑变性的预防和治疗提供新思路.

关 键 词:干性年龄相关性黄斑变性  玻璃疣  地图样萎缩  细胞治疗  基因治疗

Pathogenesis and treatment of dry age-related macular degeneration
ZHANG Jingfa,ZHANG Yumeng,SUN Xiaodong. Pathogenesis and treatment of dry age-related macular degeneration[J]. Recent Advances in Ophthalmology, 2022, 0(3): 169-178. DOI: 10.13389/j.cnki.rao.2022.0035
Authors:ZHANG Jingfa  ZHANG Yumeng  SUN Xiaodong
Affiliation:Department of Ophthalmology,Shanghai General Hospital (Shanghai First People’s Hospital),Shanghai Jiao Tong University,School of Medicine,Shanghai 200080,China
Abstract:
At present, there are no effective treatments available for dry age-related macular degeneration (dry AMD), but recent clinical trials have shown great therapeutic promise, such as dietary therapy, antibody therapy, gene therapy, cell therapy, and laser therapy. This paper summarizes the pathological characteristics, pathogenesis, and therapies of dry AMD, aiming to provide new opinions for the prevention and treatment of dry AMD.
Keywords:dry age-related macular degeneration   drusen   geographic atrophy   cell therapy   gene therapy
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