匐行性血管瘤三例并文献复习

报道本院诊断的3例匐行性血管瘤(AS),并在“中国知网、PUBMED”对近20年来公开发表的关于AS的中英文文献进行回顾分析，以期提高临床医生对该疾病的认识。结果共分析122例AS患者，男女比例为1∶1.8,平均发病年龄为12.4岁，18岁前发病者占79.6%,单侧发病者占69.7%,主要表现为多个针头大小红色或紫红色斑点，散在或簇集，以匐行、环形或线形模式发展。组织病理显示表皮大致正常，真皮浅层毛细血管扩张和(或)增生，无含铁血黄素沉积、红细胞外溢及炎细胞浸润。皮肤镜显示多个边界清楚的圆形至椭圆形红色泻湖。治疗主要以血管激光为主，尤其是脉冲染料激光，显示良好的反应性。

Angioma serpiginosum: three cases report and literature review

We report 3 cases of angioma serpiginosum (AS) diagnosed in our hospital and reviewed the related literature from CNKI and PUBMED database, in order to increase the knowledge of this disease. The result showed a total of 122 AS patients were analyzed, the ratio of male to female was 1:1.8. The average age of onset was 12.4 years old. The age of onset in 79.6% patients were younger than 18 years old. 69.7% patients had unilateral lesions which manifested as multiple pinhead-size red or purplish red spots, scattered or clustered, in the pattern of serpentine or ring development. Histopathology showed that the epidermis was generally normal, with dilatation and/or hyperplasia of capillaries in the superficial dermis, without hemosiderin deposition or erythrocyte extravasation and inflammatory cell infiltration. The dermoscope showed multiple well-defined red lagoons from round to oval. The treatment was mainly treated with vascular laser and showed good efficacy.