伽玛刀治疗血管性病变后脑水肿发生率的分析

目的探讨不同的血管性疾病γ刀治疗后脑水肿的发生率。方法回顾十余年内经γ刀治疗的血管性病变358例,采用χ^2检验探讨γ刀术后不同血管性病变及不同随访时间脑水肿发生率的差异性。结果γ刀术后,动静脉畸形（AVM）组水肿阳性率为47.5%,海绵状血管瘤组为25.9%,术后水肿发生率有显著性差异（P〈0.01）。不同随访阶段水肿阳性率分别为：≤1年为47.3%,1～3年为38.0%,3～5年为37.1%,〉5年为25.0%,不同随访阶段脑水肿发生率有显著性差异（P〈0.01）。结论脑水肿是γ刀治疗后最重要的并发症之一,术后1年内水肿的发生率最高。

The clinic analyses of the incidence rate of vascular disease' brain edema treated by Gamma Knife

Objective To study the incidence rate of brain edema of vascular disease treated by Gamma Knife.Methods To review the characters of brain edema of 358 cases treated by Gamma Knife for ten years and to find the different incidence rate of vascular disease.Results After treated by Gamma Knife,the positive rate of arterioavenous malformation(AVM) group was 47.5%,and that of cavernoma group was 25.9%.There was remarkable significance between the incidence rate of brain edema and cavernoma(P<0.01).In different followed period,the positive rate of brain edema of vascular disease was separately.That was 47.3% in 1 year,38.0% between 1~3 years,37.1% between 3~5 years,and 25.0% beyond 5 years.The incidence rate of brain edema in different followed period had remarkable significance(P<0.01).Conclusion Brain edema is one of the most important complications after treated by Gamma Knife.The tiptop of brain edema' incidence rate is in the first year.