阿替卡因与普鲁卡因麻醉下拔牙的随机对照临床试验

目的：比较阿替卡因（碧兰麻）与普鲁卡因在拔牙术中的麻醉效果，为临床推广应用提供依据。方法；112例患者的142颗患牙随机分为两组，分别进行粘膜下浸润麻醉和神经阻滞麻醉，对其麻醉注射时及拔牙时疼痛程度、麻醉持续时间进行分析。结果：阿替卡因局部浸润麻醉时注射疼痛明显小于普鲁卡因；拔疼痛程度小于或趋向小于普鲁卡因，麻醉良好率为91.7%；阻滞麻醉时麻醉持续时间明显长于普鲁卡因。结论：阿替卡因忆部渗透力强，浸润麻醉安全、有效，阻滞麻醉可持续较长时间，是一种高效的口腔科专用局部麻醉剂。

A random contrast clinical trial of local anesthesia in extraction of teeth with articaine and procaine

Objectives:To compare the efficacy of local anesthesia using 4% articaine and 2% procaine in extraction of teeth. Methods:One hundred and twelve patients(142 teeth) were selected and divided into two groups. They were randomly applied by submucous infiltration anesthesia or nerve block anesthesia by using articaine or procaine in extraction of teeth. The degree of pain during the injection and extraction of teeth and the persistent time of the anesthesia were then observed and analyzed. Results:The pain degree of anesthesia using articaine was much slighter than that of procaine during the injection and extraction of teeth( P <0.01), and the persistent time of anesthesia of articaine was lo nger than that of procaine. The well anesthesia rat was 91.7%. Conclusions:Articaine is a safe and effective anesthetic medicine for oral surgery.