围产期高危儿早期干预的效果评价

的：评价早期干预对防治围产期高危儿神经系统生长发育异常的临床价值。方法：所有高危儿进行早期干预。新生儿期采用NBNA法进行评价,婴儿期采用52项神经运动检查法进行评价。同时进行体格测定。结果：纠正年龄l周及4周时，高危儿组除高胆红素血症组患儿（P〉0．05）外，其他各因素高危患儿组NBNA评分与正常儿组之间差异均有显著性（P〈0．05）。生后l周及4周比较各组新生儿NBNA评分均获得显著进步（P〈0，05）。在婴幼儿期，随着干预的进行，高危儿各组与正常儿组之间神经运动发育的差距逐渐缩小，且高胆红素血症组有超前现象。在体重、身高、头围方面，高危儿各组除高胆红素血症组外在3个月时与正常儿组比较仍存在明显差异（P〈0．05），经过干预，于12个月时与正常儿组比较差异无显著性（P〉0．05）。结论：早期干预治疗效果显著

Effects of early intervention on high-risk infants of perinatal period

Objective To evaluate the effect of early intervention in the prevention and treatment of abnormal development of nervous system in high-risk infants. Methods The high-risk infants underwent early intervention. Neonates were evaluated by NBNA method. Babies who were not less than one month were evaluated by 52-neuro-motorial examination. In addition, physique development was checked. Results Whether the once week or fourth week, there was significant difference of the NBNA score between the normal-baby group and every high-risk-infant groups(P < 0.05) except the hypercholesterolemia group(P > 0.05). For every group, the NBNA score more increased significantly (P < 0.05) in 4th week than in 1st week. In nervous-motor development, the deference between every high-risk-infant groups and the normal-baby group became more and more small with intervention prolongation, and infants in the hypercholesterolemia group had an advantage over the normal-baby group. In addition, there were significant deference in physique development between each group of the high-risk-infant groups and the normal-baby group when they were 3 months old (P < 0.05),however, there were no significant deference between them after intervention when they were 12 months old (P > 0.05). Conclusion: Early intervention was effective in treating high-risk infants.