广州地区1 530例骨密度分析及骨质疏松发病率研究

目的为了解广州地区正常人群骨密度(BMD)的变化规律和骨质疏松(OP)的患病率.方法采用美国Lunar公司的双能X线骨密度仪对广州地区1 530名20～89岁居民进行腰椎2-4和髋部骨密度测量.结果男性腰椎骨密度峰值在20～29岁,女性腰椎骨密度峰值在30～39岁,男性与女性髋部骨密度峰值均在30～39岁,峰值后随年龄增加而骨密度下降,女性在50～59岁出现明显加速,男性没有加速下降现象.广州地区男性50～89岁骨质疏松患病率26.53%,女性50～89岁骨质疏松患病率42.64%,两者之间差异有非常显著性(P＜0.01).结论广州地区女性骨质疏松患病率高于男性,预防骨质疏松的重点在女性,但对男性骨质疏松患者也不容忽视.

Measurement of bone mineral density by DEXA and prevalence rate of osteoporosis in 1 530 Guangzhou residents

Objective To analyze the regularities of changes in bone mineral density(BMD) and the prevalence rate of osteoporosis(OP) Methods The BMD of L 2 4 and hip were measured by Lunar Plus dual enengy X ray absorptiometry(DEXA)for 1 530 people(755 men and 775 women, aged 20 89 years) Results The BMD peak values of L 2 4 were seen in 20 year old group for males and in 30 year old group for females However, the peak bone mass of hip was found in 30 year old groups of both sexes Afterwards, BMD diminished with increasing age The bone loss was sharply decreased for females after 50 years of age, but that of males was progressive and slow The prevalence rate of osteoporosis in residents aged 50 89 years old was 26 35% for men and 42 64% for women in Guangzhou district ( P <0 01) Conclusion The prevalence of osteoporosis in female was higher than that of male in Guangzhou The prevention and treatment of osteoporosis are very important to the female but should not be ignored in male