Immunohistochemical localization of androgen and progesterone receptors in the uterus of the camel (Camelus dromedarius) |
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Affiliation: | 1. College of Veterinary Science and Medicine, Central Luzon State University, Science City of Muñoz, 3120 Nueva Ecija, Philippines;2. Animal Health Unit, Philippine Carabao Center National Headquarters and Gene Pool, Science City of Muñoz, 3120 Nueva Ecija, Philippines;3. Affiliate Faculty, Department of Animal Science, Institute of Graduate Studies, Central Luzon State University, Science City of Muñoz, 3120 Nueva Ecija, Philippines;1. Division of Anatomy, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania;2. MEDCENTER, Center of Excellence in Laboratory Medicine and Pathology, Bucharest, Romania;3. International Society of Regenerative Medicine and Surgery (ISRMS), Romania;4. Department of Medicine and Surgery, University of Catania, Italy;5. Division of Ophthalmology, S.C.U.O., Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania;6. Clinical Hospital of Ophthalmologic Emergencies (S.C.U.O.), Bucharest, Romania;1. Department of Brain Physiology, State Key Laboratory of Molecular and Cellular Biology, Bogomoletz Institute of Physiology, National Academy of Sciences, Bogomoletz Str. 4, Kiev 01024, Ukraine;2. Laboratory of Experimental Neurophysiology, Pirogov National Medical University, Ministry of Public Health of Ukraine, Pirogov Str. 56, Vinnitsa 21018, Ukraine;3. Department of Movement Physiology, Bogomoletz Institute of Physiology, National Academy of Sciences, Bogomoletz Str. 4, Kiev 01024, Ukraine;1. Faculdade de Medicina de São José do Rio Preto (FAMERP), Laboratório de Investigação Molecular do Câncer (LIMC), Sao Jose do Rio Preto, Sao Paulo 15090-000, Brazil;2. Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP/IBILCE), Program of Post-Graduate in Genetics, Sao Jose do Rio Preto, Sao Paulo 15054-000, Brazil |
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Abstract: | ![]() Ten adult, cyclic female camels (Camelus dromedarius) were used to describe the distribution of androgen (AR) and progesterone (PR) receptors in the uterus using immunohistochemistry. Both AR and PR were distributed throughout the different compartments of the uterus with nuclear staining for AR and PR seen in the cells of epithelia (luminal and glandular), stroma and myometrial smooth muscles. AR immunostaining was not uniform in distribution and intensity; the surface epithelium and the glandular epithelium in the adluminal region of the endometrium showed lower AR immunoreactivity than other compartments of the uterus. PR immunostaining showed uniformity in both distribution and intensity strong PR immunostaining intensity in almost all cells of the different uterine compartments. The intensity and distribution of PR immunostaining in epithelia of lumen and glands in the adluminal regions of endometrium was higher (P < 0.05) than that of AR. In conclusion, immunohistochemical localization of AR and PR in the uterus of the cyclic dromedary camel indicates the important roles of androgen and progesterone in controlling the uterine activity during the follicular phase. |
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Keywords: | Androgen receptor Progesterone receptor Immunohistochemistry Uterus Camel |
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