停乳链球菌似马亚种感染致新生儿化脓性脑膜炎一例

本文报告了1例停乳链球菌似马亚种感染致新生儿化脓性脑膜炎病例的诊治经过。该例患儿系18 d女婴,因发热7 h入院。入院后经查血常规及超敏C-反应蛋白、降钙素原、脑脊液、血培养等,诊断为新生儿化脓性脑膜炎。给予敏感抗生素抗感染,以及镇静止惊、降颅内压、补液等综合治疗4周后,患儿治愈出院。出院1月余门诊随访,其生长发育正常,头颅MRI未见异常,听力亦未见异常。由本例认为,停乳链球菌似马亚种感染发病时间短、病情重且进展快。

Neonatal purulent meningitis due to Streptococcus dysgalactiae subsp.equisimilis infection:a case report

We reported the diagnosis and treatment of one neonate with purulent meningitis caused by Streptococcus dysgalactiae subsp.equisimilis infection.The eighteen-day-old girl was admitted due to fever lasting for seven hours and was diagnosed as neonatal purulent meningitis based on laboratory tests,including the routine blood test,hypersensitive C-reactive protein,procalcitonin,cerebrospinal fluid examination,and blood culture.The patient recovered and was discharged after a four-week comprehensive treatment,including antibiotics,sedatives,lowering intracranial pressure and rehydration and fluid replacement.During the follow-up of one month after discharge,the girl showed normal growth and development without any abnormality in cranial MRI or hearing.This case suggested that Streptococcus dysgalactiae subsp.equisimilis infection has a quick onset with serious conditions and rapid progress.