Fetal MRI of the central nervous system: State-of-the-art |
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| Affiliation: | 1. Academic Unit of Radiology, University of Sheffield, Sheffield, UK;2. Clinical Trials Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK;3. INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield, UK;4. Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK;5. Newcastle University, Newcastle upon Tyne, UK;6. Centre for Women''s and Newborn Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK;7. Fetal Medicine Centre, Birmingham Women''s Foundation Trust (Birmingham Health Partners), Birmingham, UK;8. Leeds Teaching Hospitals NHS Trust, Leeds, UK;1. Clinic of Obstetrics and Gynecology, Ospedale della Murgia, Bari, Italy;2. Maternal-Fetal Medicine Unit, Department of Obstetrics and Gynecology, University of Brescia, Brescia, Italy;1. Aix Marseille University, Marseille, France;2. National Autonomous University of Mexico, Mexico City, México |
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| Abstract: | ![]()
Prenatal ultrasonographic (US) examination is considered as the first tool in the assessment of fetal abnormalities. However, several large-scale studies point out that some malformations, in particular central nervous system (CNS) anomalies, are not well characterized through US. Therefore, the actual malformation severity is not always related to prenatal ultrasound (US) findings.Over the past 20 years, ultrafast Magnetic Resonance Imaging (MRI) has progressively increased as a prenatal 3rd level diagnostic technique with a good sensitivity, particularly for the study of fetal CNS malformations. In fact, CNS anomalies are the most common clinical indications for fetal MRI, representing about 80% of the total examinations.This review covers the recent literature on fetal brain MRI, with emphasis on techniques, safety and indications. |
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| Keywords: | Fetal MRI MRI Prenatal CNS malformation Congenital CNS abnormality Fetal anomalies CNS |
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