单纯室间隔缺损的产前及产后超声诊断分析

目的 探讨单纯性室间隔缺损产前及产后超声表现的差异。方法 回顾性分析244例单纯性室间隔缺损患儿超声心动图资料，对患儿随访至出生后1年。与产后结果对比，将产前检查的胎儿分为正确组和错误组，评价室间隔缺损类型、大小及心室水平分流情况并进行统计学分析。结果 244例患儿中，正确组181例，错误组63例；两组缺损类型差异无统计学意义（P=0.061）；两组产后缺损大小和分流速度差异有统计学意义（P均<0.05），分流方向差异无统计学意义（P=0.408）；正确组产前和产后缺损大小差异有统计学意义（P<0.05），分流方向差异无统计学意义（P=0.087）。结论 产前超声可检出单纯性室间隔缺损，缺损本身的解剖特点可能影响产前检查结果，同一病变产前产后超声表现差异明显。

Antepartum and postpartum echocardiographic diagnosis of isolated ventricular septal defect

Objective To investigate the differences between prenatal and postnatal ultrasound findings in isolated ventricular septal defects. Methods Totally 244 cases of isolated ventricular septal defect were retrospectively analyzed and followed in one year after birth. All fetus were divided into the correct group and the error group according to the postnatal results. The size and type of ventricular septal defect and ventricular shunt were assessed and analyzed statistically. Results In all of the 244 cases, correct group included 181 cases and error group included 63 cases. There was no significant difference in the type of defects between two groups (P=0.061); there were significant differences in the size of postpartum defect and the velocity of ventricular shunt between the two groups (both P<0.05), and no significant difference of the direction of shunt between two groups (P=0.408); there were significant differences in the size of defects between the prenatal and postnatal in correct groups (P<0.05), but the direction of shunt had no significant difference (P=0.087). Conclusion There is certain detection rate in prenatal diagnosis of isolated ventricular septal defect; anatomical characteristics of defect may affect antenatal examination results. There was significant difference between prenatal and postnatal ultrasound in the same lesion.