脑卒中后抑郁相关问题的探讨

目的：研究卒中后抑郁（post-stroke depression,PSD）相关因素,初步探讨PSD发病机制,提供其可能的预测因素,并依照相关因素制定相应护理对策。方法：根据汉密尔顿抑郁量表（HAMD）得分将104例脑卒中住院病人分为抑郁组和非抑郁组,对PSD发生可能相关的15个因素进行单因素相关分析探讨PSD发生的相关因素;然后将抑郁组随机分为护理干预组和非护理干预对照组,观察护理干预对PSD影响。结果：PSD总发病率46.1%;神经功能缺损评分、病变部位、对陪护人员的满意程度、社会支挣隋况、性格特征等因素与PSD发生密切相关;护理干预4周后干预组较非干预组HAMD评分改善具有统训学意义（P〈0.05）。结论：PSD的发生是神经生物学因素和社会心理学因素共同作用的结果,恰当护理能改善PSD症状。

The discussion of correlation factors in post-stroke depression

Objective:To investigate the pathogenesy of post-stroke depression (PSD) and provide possible prediction for PSD,we researched the relative factors in PSD.Then according to the relative factors,we applied strategies for nursing intervention.Methods:According to Hamilton Depression Rating Scales (HAMD),104 inpatients after stroke were assessed to divide into two groups,PSD group and non-PSD group.The one way ANOVA statistics was carried out to analysis possible 15 relative factors in PSD.Then PSD group was randomly divided into two groups according to applying nursing intervention to observe the effect of nursing intervention for PSD.Results:The incidence of PSD was 46.1%.PSD was correlated closely with neurologic impairment score, diseased region,patients content degree to care,social support and character trait.After 4 weeks,HAMD scores in nursing intervention group were significant improve than PSD patients without nursing intervention (P<0.01). Conclusion:Neurobiological factor and social psychological factor are co-effect to the incidence of PSD and appropriate nursing intervention could relieve symptom of PSD.