| 血管内皮生长因子在乳腺癌中的表达及其临床意义 |
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| 引用本文： | 杜金荣,张艳梅,付红,薛玉华. 血管内皮生长因子在乳腺癌中的表达及其临床意义[J]. 哈尔滨医科大学学报, 2000, 34(5): 341-342 |
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| 作者姓名： | 杜金荣 张艳梅 付红 薛玉华 |
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| 作者单位： | 哈尔滨医科大学附属第二医院,病理科,黑龙江,哈尔滨,150086;哈尔滨医科大学附属第二医院,病理科,黑龙江,哈尔滨,150086;哈尔滨医科大学附属第二医院,病理科,黑龙江,哈尔滨,150086;哈尔滨医科大学附属第二医院,病理科,黑龙江,哈尔滨,150086 |
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| 摘 要： | 目的 研究血管内皮生长因子（ＶＥＧＦ）在乳腺癌的发生及判断预后方面的意义。方法 应用Ｓ－Ｐ免疫组化染色法检测ＶＥＧＦ在乳腺良恶性病变中的表达。结果 乳腺癌ＶＥＧＦ表达阳性率（７２．５％）高于乳腺良性病变（２／８）,二者间差异具有显著性（Ｐ〈０．０５）。４０例乳腺癌中,淋巴结转移组ＶＥＧＦ阳性表达（１９／２１）高于淋巴结转移组（１２／１９）,二者差异具有显著性（Ｐ〈０．０５）。结论 ＶＥＧＦ在乳腺癌
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| 关 键 词： | 血管内皮生长因子 乳腺癌 免疫组化方法 |
The expression and clinical significance of vascular endothelial growth factor in breast cancer |
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| DU Jin rong,ZHANG Yan mei,FU Hong,et al. The expression and clinical significance of vascular endothelial growth factor in breast cancer[J]. Journal of Harbin Medical University, 2000, 34(5): 341-342 |
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| Authors: | DU Jin rong ZHANG Yan mei FU Hong et al |
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| Abstract: | Objective To study the role of vascular endothelial growth factor (VEGF) in development and evaluating prognosis of breast cancer. Methods S P immunohistochemical method was used to detect VEGF expression in breast benign and malignant disease. Results VEGF expression positive rate in breast cancer (72.5%) was higher than that in breast benign disease (2/8), the difference was significant ( P <0.05). In 40 cases of breast cancer, the expression of VEGF in lymphatic metastasic group (19/21) was more than that in none lymphatic metastasic group(12/19), the difference was significant ( P <0.05). Conclusion VEGF play an important role in development and evaluating prognosis of breast cancer. |
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| Keywords: | vascular endothelial growth factor breast cancer immunohistochemical method |
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