电浮针对原发性痛经镇痛作用的随机对照研究

目的:观察电浮针疗法对原发性痛经(PD)的镇痛作用及临床疗效。方法:171例PD患者,随机分为电浮针组、浮针组和药物组各57例,电浮针组采用电针刺激(疏波频率约60 Hz、串长2.5 s,密波频率约60 Hz、串长5 s,强度2~3 V,持续30 min)与浮针疗法相结合,远取三阴交穴治疗,浮针组采用浮针疗法取三阴交穴治疗,药物组采用口服布洛芬缓释胶囊(0.3 mg/次,2次/日)治疗,3组均连续治疗3个月经周期,治疗后随访3个月经周期统计疗效。结果:纳入171例患者,163例完成试验,脱落8例。电浮针组、浮针组与药物组总有效率(ITT/PP)分别为94.74%/96.43%、91.23%/96.30%和77.19%/83.02%;电浮针组:近期治愈40/40,显效9/9,好转5/5,无效3/2;浮针组:近期治愈38/38,显效10/10,好转4/4,无效5/2;药物组:近期治愈10/10,显效27/27,好转7/7,无效13/9。ITT和PP分析结果一致:电浮针和浮针组的总疗效以及痊愈率显著优于药物组(P<0.01),电浮针与浮针组的总疗效以及痊愈率差异无显著性意义;短时间内电浮针组镇痛作用优于浮针组(P<0.05)。结论:三阴交穴电浮针疗法对PD的镇痛作用具有高效快捷、安全无痛的特点,临床疗效显著优于口服布洛芬缓释胶囊。

Randomized Controlled Study on the Analgesic Effect of Superficial Needling plus Electrostimulation of Sanyinjiao (SP 6) for Primary Dysmenorrhea

Objective: To evaluate the analgesic and therapeutic effects of electro-superficial-acupuncture(ESA) of Sanyinjiao(SP 6) for treating primary dysmenorrhea(PD).Methods: A total of 171 patients were randomly divided into ESA(n=57),superficial acupuncture(SA)(n=57) and medication(n=57) groups.For patients in SA group,bilateral SP6 were punctured superficially with special single-use needles,and for those in ESA group,after puncturing,electric stimulation(60 Hz,2-3 V) was applied to SP6 for 30 min.Patients of medication group were ordered to take Brufen sustained-release capsules(0.3 mg,b.i.d.,for 3 days),then,take it again from the 3rd day on before the onset of menstruation to the 2nd day after the onset.The cumulative score of clinical symptoms were evaluated before and after the treatment.Results: Comparison among 3 groups showed that the difference values of score(pre-treatment-post-treatment) of both ESA and SA groups were significantly bigger than that of medication group(P<0.001).After the treatment from 1 min to 30 min,patients with complete relief of dysmenorrhea of ESA group were significantly more than those of SA group during the 1st menstrual cycle(P<0.05).Results of intention-to-treat(ITT) analysis showed that of the three 57 cases in ESA,SA and medication groups,the cured cases were 40,38 and 10,the markedly effective were 9,10 and 27,the effective were 5,4 and 7,and the failed were 3,5 and 13,with the total effective rates being 94.74%,91.23% and 77.19% respectively.The effective rates of ESA and SA groups were significantly higher than that of medication group(P<0.01),and the results of per-protocol analysis(PP) were similar to those of ITT analysis.Conclusion: The analgesic effect of both ESA and SA at SP6 for PD patients is significantly better than that of oral administration of Brufen.