肝囊型包虫病药物治疗中B超影像动态观察及分类建议

目的在确定肝囊型包虫病B超影像特征及其分布的基础上,系统观察阿苯达唑乳剂治疗期间包虫囊影像变化动态及其与疗效的关系,提出可用于药物治疗中疗效判定的影像分类方法。方法对497例初诊的肝囊型包虫病患者共645个包虫囊的B超影像进行分类,观察不同影像类型在患者群体中的分布。结合212例肝包虫病患者在药物治疗过程中影像变化的规律进行比较分析,探讨影像类型与临床疗效的对应关系。结果将肝囊型包虫病患者包虫囊的B超影像分为6型。各型影像在患者中的分布反映了包虫囊在人体内的自然演变过程。在药物治疗期间包虫囊的影像变化动态与自然演变过程相符。结论本文提出的影像分类反映了包虫囊在人体内经历的从生长发育到衰老死亡的缓慢过程。药物治疗期间包虫囊的影像变化证明药物作用加速了这个过程。影像分类方法可用于腹部包虫病的诊断和药物治疗效果评价。

Dynamic Observation on Ultrasonographic Image During Chemotherapy of Hepatic Cystic Echinococcosis and a Proposal for Ultrasonic Classification

Objective To submit a proposal for the classification of ultrasonographic image in patients with hepatic cystic echinococcosis, on the basis of characteristic and distribution of ultrasonic image of hydatid cysts in cases and systematic observation on dynamic changes of sonographic image under treatment with emulsion albendazole and in relation to clinical efficacy. Methods The ultrasonic image of 645 cysts in 497 cases with liver cystic echinococcosis was classified. The distribution of different types of image in patients was analyzed. A comparative analysis of correspondence between the sonographic type and clinical efficacy was made in association with the rule of changes in ultrasonic features during chemotherapy. Results The ultrasonographic image of hydatid cysts was divided into six types. The distribution of ultrasonic types in patients reflected the process of natural evolution of cysts in human bodies. The dynamic change of ultrasonic image during treatment was identical with the natural evolution process of hydatid cysts. Conclusion The proposal for ultrasonographic classification submitted reflects a long evolutionary process from growth to death of hydatid cysts in human body. The dynamic change of hydatid cysts during chemotherapy indicated that the effect of drug has accelerated this process. Therefore this classification may be applied in diagnosis and to judge the chemotherapeutic efficacy of cystic echinococcosis.