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Influence of early maternal deprivation on adult humoral immune response in mice |
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| Authors: | Rene-Jean Michaut Roger-Paul Dechambre Severin Doumerc Bruno Lesourd Andree DeVillechabrolle Robert Moulias |
| Affiliation: | Unité de réanimation hémato-cancérologique Institut de Cancérologie et d''Immunogénétique, F 94800 Villejuif, France;Service d''Expérimentation animale Institut Gustave-Roussy, F 94800 Villejuif, France;Laboratoire d''Immunologie, CHU Pitié-Salpêtrière, F 75013 Paris, France |
| Abstract: | Mice were submitted to early maternal deprivation before weaning and were weaned earlier than the usual age. When adult, those mice showed decreased number of PFC and lowered level of seric immuno-globulins compared with controls. Two etiogenic hypothesis are discussed: undernourishment and adrenal stress. |
| Keywords: | Maternal deprivation Plaque forming cells Immuno-globulins Mice |
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