| 冷束缚应激大鼠十二指肠电-机械活动变化 |
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| 引用本文： | 李利生,曲瑞瑶,王伟,郭华,孟旸.冷束缚应激大鼠十二指肠电-机械活动变化[J].首都医学院学报,2002,23(4):300-302. |
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| 作者姓名： | 李利生 曲瑞瑶 王伟 郭华 孟旸 |
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| 作者单位： | 首都医科大学生理学教研室
(李利生，曲瑞瑶，王伟，郭华)，首都医科大学生理学教研室(孟旸) |
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| 基金项目： | 1999-2 0 0 0年度北京中医局科技发展基金资助课题 |
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| 摘 要： | 用双银球电极 应变片记录了冷束缚应激大鼠十二指肠的电 机械活动 ,发现冷束缚应激大鼠十二指肠慢波平均频率降低 ,平均振幅降低 (P <0 .0 0 1 ) ;十二指肠运动频率降低 ,振幅增加 (P <0 .0 0 1 ) ;十二指肠慢波及运动的频率和振幅变异系数都增加 ;移行性复合运动 (MMC)周期缩短。结合本室冷束缚应激大鼠肠道P物质 (SP)和血管活性物质 (VIP)含量的变化及其他研究结果 ,提示 :冷束缚应激大鼠十二指肠电 机械活动变化与十二指肠SP、VIP等含量改变可能具有机制上的密切联系
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| 关 键 词： | 冷束缚应激 十二指肠 电-机械活动 |
| 收稿时间： | 2002-07-12 |
| 修稿时间： | 2002年7月12日 |
Changes of Electro-mechanical Activity in Duodenum of Cold Restraint Stress Rats |
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| Li Lisheng,Qu Ruiyao,Wang Wei,Guo Hua,Meng Yang.Changes of Electro-mechanical Activity in Duodenum of Cold Restraint Stress Rats[J].Journal of Capital University of Medical Sciences,2002,23(4):300-302. |
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| Authors: | Li Lisheng Qu Ruiyao Wang Wei Guo Hua Meng Yang |
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| Institution: | Li Lisheng,Qu Ruiyao,Wang Wei,Guo Hua,Meng Yang Department of Physiology,Capital University of Medical Sciences |
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| Abstract: | The aim of this study is to investigate mechanisms of duodenal motility disorders presented in cold restraint stress rats by using electrode and highly sensitive sensor to record alterations of duodenum electromechanical activity. The study suggested that the average frequency and amplitude of duodenal slow wave was lower than the control group( P <0.001); Duodenal motion frequency of cold restraint stress rats was lower than that of the control groups ( P <0.001), while motion amplitude was higher than that of the control groups. The time of MMC was obviously less than the control group. The results showed that changes of electro mechanical activity in duodenum of cold restraint stress rat and gastrointestinal peptides may be related to the gastrointestinal motility disorders presented in cold restraint stress rats. |
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| Keywords: | cold restraint stress duodenum electro mechanical activity |
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