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定量组织速度成像评价动脉粥样硬化家兔左室舒张功能的实验研究
引用本文:陈瑶,常培叶. 定量组织速度成像评价动脉粥样硬化家兔左室舒张功能的实验研究[J]. 内蒙古医学杂志, 2007, 39(12): 1420-1421
作者姓名:陈瑶  常培叶
作者单位:内蒙古医学院基础医学院病理生理教研室,内蒙古,呼和浩特,010059;内蒙古医学院基础医学院病理生理教研室,内蒙古,呼和浩特,010059
摘    要:
目的:应用超声定量组织速度显像(QTVI)技术评价动脉粥样硬化家兔左室舒张功能。方法:24只雄性日本大耳白兔随机分为对照组8只和实验组16只,实验组以高脂饲料饲养建立动物模型。实验组在高脂饲料饲养的8、12周测定二尖瓣环舒张早期平均峰值速度(Em)及舒张晚期平均峰值速度(Am),将Em/Am的比值进行显著性比较。结果:实验组在高脂饲料饲养的12周,Em/Am与对照组相比差异具有显著性(P<0.01)。结论:QTVI技术可以实时、客观地评价动脉粥样硬化家兔的左室功能。

关 键 词:动脉粥样硬化  左室舒张功能  定量组织速度成像
文章编号:1004-0951(2007)12-1420-02
修稿时间:2007-11-10

Experiment Study on Evaluation of Left Ventricular Diastolic Function by Quantitative Tissue Velocity Imaging in Rabbits with Aherosclerosis
Chen Yao,CHANG Pei-ye. Experiment Study on Evaluation of Left Ventricular Diastolic Function by Quantitative Tissue Velocity Imaging in Rabbits with Aherosclerosis[J]. Inner Mongolia Medical Journal, 2007, 39(12): 1420-1421
Authors:Chen Yao  CHANG Pei-ye
Abstract:
Objective:To evaluate the left ventricular diastolic function by quantitiative tissue velocity imaging(QTVI).Methods:24 female rabbits were randomly divided into control group(n=8) and experiment group(n=16).The animal model in experiment group was established with high fat feeds.In animals in experiment group,the peak velocity of early average diastolic E wave and late average diastolic E wave were measured at 8 and 12 week,then compared Em/Am. Results: At 12 week,the Em/Am showed significantly different between experiment group and control group(P<0.01).Conclusion: QTVI technique is feasible and objective in evaluating the left ventricular function in rabbits with atherosclerosis.
Keywords:Atherosclerosis  Left ventricular diastolic function  Qantitiative tissue velocity imaging(QTVI)
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