106例肥胖儿童非酒精性脂肪肝病临床分析

目的探讨肥胖儿童非酒精性脂肪肝（nonalcoholic fatty liver disease,NAFLD）临床特点及高危因素,为NAFLD的预防和治疗提供帮助。方法分析我院2009年12月-2011年12月收治的106例非酒精性脂肪肝的临床资料,统计其性别、年龄、体重指数（BMI）、空腹胰岛素及甘油三酯结果,并分析体重指数（BMI）、空腹胰岛素及甘油三酯与NAFLD发生的相关关系。结果 106例患儿中,男女发病年龄分布未见统计学差异（P〉0.05）;体重指数（BMI）及甘油三酯是NAFLD发生的高位因素（P〈0.05）,而空腹胰岛素水平与NAFLD发生无明显相关关系（P〉0.05）。结论 NAFLD多发生于男性患儿;NAFLD的发生受到多种因素影响,但体重指数（BMI）及甘油三酯是主要的相关危险因素。

Clinical analysis of nonalcoholic fatty liver disease in 106 cases children with obesity

Objective To explore the high risk factors and clinical problems on nonalcoholic fatty liver disease in children with obesity.Methods Data of 106 cases of adiposity with nonalcoholic fatty liver disease,from December 2009 to December 2011,were summarized.The influences of factors such as age,gender,body mass index(BMI),duration of diabetes and glycerin trilaurate level were statistically analyzed.Results In those persons with NAFLD,80 cases were male,the others femalel;the distributing of age have no statistical differences betwween male and female(P>0.05);Body mass index and glycerin trilaurate level were the factor related to the outcomes of the patients(P<0.05);Duration of diabetes was not the factor related to the outcomes of the patients(P>0.05).Conclusion The man children is predispose to NAFLD;actually,NAFLD are governed by many factors,and Body mass index and glycerin trilaurate level were the main risk factor.