流行性出血热实验室早期诊断的探讨

本文采用EHFRS25—1MCAb—FITC法检测50例发病一周内的流行性出血热患者血、尿细胞抗原。阳性率为:淋巴细胞82％、中性粒细胞80％、尿沉渣细胞75％。病程与阳性率有明显的关系;第二病日阳性率已为50％,第3～4病日高达90.90％～92.85％,对照组均阴性。同步测血清抗体(IgG)阳性率仅42％。结果表明本实验方法对临床早期诊断及进一步研究本病发病机理有重要意义。

Study on the Early Laboratory Diagnosis of Epidemic Hemorrhagic Fever

The antigens in the cells of blood and urine sediment of 50cases with epidemic hemorrhagic fever were examined and measured by EHFRS 25-1 McAb-FlTc.It was done in. the first week of the course of the disease, the positive rate was 82% in Lymphocytes, 80% in newtrophil granulocytes and 75% in the cells of urine sediment.The results revealed that there was an evident relationship between the course and the positive rates of the disease.The positive rate in the second day of attack was 50%, it then elevated to 90.90～92.85% in the third and fourth day. There were negative results in the control.The positive rate serum antibody (IgG) was only 42% measured in the same time. It showed that this method has an important significance to the early diagnosis and the further study on the mechanism of the disease.