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Value of diffusion weighted magnetic resonance imaging in grading of urinary bladder carcinoma
Authors:Eman Muhammad Abdelsalam  Mohamed Ali EL Adalany  Mohamed Elsayed Ahmed Fouda
Affiliation:1. Department of Diagnostic Radiology and Medical Imaging, Faculty of Medicine, Mansoura University, Eqypt;2. Department of Diagnostic Radiology and Medical Imaging, Urology and Nephrology Center, Mansoura University, Eqypt
Abstract:
Aim of the study: to evaluate the role of diffusion weighted magnetic resonance imaging in urinary bladder cancer grading in comparison to histopathological grading.

Patients and methods

This prospective study included 50 patients; 30 males and 20 females with mean age 66.4?years. All patients were referred clinically for bladder cancer and hence all of them underwent MR imaging. T2 weighted images were acquired followed by diffusion study in the same plane, b value?=?800?s/mm2.

Results

pathologic staging was between Tis and T1 (superficial) in 28% of tumors. More than T1 (Deep) in 72%. The mean ADC value was 1.203?×?10–3 with a standard deviation of ±0.385?×?10–3. The mean ADC value for stages Tis to T1 tumors was 1.505?×?10–3?±?0.270 SD; and stages T2 to T4 tumors was 1.085?±?0.385 SD; P?–3 as a useful indicator for differentiating stages Tis to T1 from T2 to T4; P?

Conclusion

DW imaging is a noninvasive reliable modality for predicting histopathological aggressiveness of bladder cancer.
Keywords:MRI  Diffusion  Urinary bladder cancer  Transitional cell carcinoma
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