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| XELOX方案与DF方案治疗老年患者晚期胃癌的比较 | |
| 引用本文： | 李尚富,韩述岭,潘春球,许琦. XELOX方案与DF方案治疗老年患者晚期胃癌的比较[J]. 现代消化及介入诊疗, 2011, 16(2): 112-114 |
| 作者姓名： | 李尚富 韩述岭 潘春球 许琦 |
| 作者单位： | 1. 湖南省岳阳市二人民医院肿瘤科,414000 2. 南方医科大学南方医院普外科,510515 3. 南方医科大学南方医院急诊外科,510515 |
| 摘 要： | 目的比较XELOX方案与DF方案对老年患者晚期胃癌的临床疗效和毒副反应。方法 46例晚期胃癌老年患者随机分为XELOX组和DF组。所有病例治疗4周期以上,按WHO标准进行评价并比较两组近期疗效及毒副反应。结果 XELOX组总有效率52.2%,DF组总有效率47.8%;两组总有效率差异无统计学意义;XELOX组手足综合征的发生率显著高于DF组（P〈0.05）,骨髓抑制的发生率显著低于DF组（P〈0.05）,其他各项常见副反应均无统计学意义（P〉0.05）。结论 XELOX方案和DF方案治疗晚期胃癌疗效相当,主要毒副反应不同,均可耐受;XELOX方案可能更易为老年患者所接受。 |
| 关 键 词： | 老年 中晚期胃癌 奥沙利铂 卡培他滨 多西紫杉醇 |
Comparison of XELOX and DF in the treatment of elderly patients with advanced gastric cancer |
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| LI Shang-fu,HAN Shu-ling,PAN Chun-qiu,XU Qi. Comparison of XELOX and DF in the treatment of elderly patients with advanced gastric cancer[J]. Modern Digestion & Intervention, 2011, 16(2): 112-114 | |
| Authors: | LI Shang-fu HAN Shu-ling PAN Chun-qiu XU Qi |
| Affiliation: | LI Shang-fu1,HAN Shu-ling2,PAN Chun-qiu3,XU Qi1.1 Department of the Second Hospital of Yueyang,Yueyang 41400,China,2 Department of General Surgery,Nanfang Hospital,Southern Medical University,Guangzhou 510515,3 Emergency Department |
| Abstract: | Objective To evaluate the efficacy and toxicity of XELOX and DF therapy in the treatment of elderly patients with advanced gastric cancer.Methods Fourty six patients with advanced gastric cancer were enrolled into this study.They were randomly divided into XELOX therapy group and DF therapy group respectively.All patients received four cycles of chemotherapy at least.The efficacy and toxicity were evaluated according to WHO standard.Results The overall effective rate in XELOX therapy group was 52.2%,and in ... |
| Keywords: | Elderly Advanced gastric cancer Oxaliplatin Capecitabine Docetaxel |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |