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| 多西他赛联合FOLFOX方案治疗进展期胃癌临床疗效观察 | |
| 引用本文： | 王思亮,陈晓东,吴荣,钱昊初. 多西他赛联合FOLFOX方案治疗进展期胃癌临床疗效观察[J]. 实用临床医药杂志, 2011, 15(9): 59-61 |
| 作者姓名： | 王思亮 陈晓东 吴荣 钱昊初 |
| 作者单位： | 中国医科大学附属盛京医院,辽宁,沈阳,110022 |
| 摘 要： | 目的观察多西他赛联合FOLFOX方案治疗进展期胃癌的疗效及不良反应。方法对32例进展期胃癌行多西他赛联合FOLFOX方案化疗,3周为1周期,完成2个周期后评价疗效。结果化疗总有效率37.5%,中位疾病进展时间6.3个月,中位生存期10.4个月。不良反应以骨髓抑制、胃肠道反应和静脉炎为主。结论多西他赛联合FOLFOX方案治疗进展期胃癌有较好的疗效,毒副作用可以耐受,可作为进展期胃癌一线治疗方案。 |
| 关 键 词： | 多西他赛 FOLFOX 进展期胃癌 |
Clinical observation of Docetaxel combined with FOLFOX on advanced gastric cancer |
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| WANG Si-liang,CHEN Xiao-dong,WU Rong,QIAN Hao-chu. Clinical observation of Docetaxel combined with FOLFOX on advanced gastric cancer[J]. Journal of Clinical Medicine in Practice, 2011, 15(9): 59-61 | |
| Authors: | WANG Si-liang CHEN Xiao-dong WU Rong QIAN Hao-chu |
| Affiliation: | WANG Si-liang,CHEN Xiao-dong,WU Rong,QIAN Hao-chu(Shengjing Hospital Affiliated to China Medical University,Shenyang,Liao Ning,110022) |
| Abstract: | Objective To evaluate the efficacy and toxicity of Docetaxel(DTX) combined with FOLFOX in treating patients with advanced gastric carcinoma.Methods Thirty-two patients were treated with Docetaxel and FOLFOX regimen,(1 cycle=every 3 weeks).Tumor assessment was done after 2 cycles.Results The overall response rate was 37.5%,and the median TTP was 6.3 months.Median survival time was 10.4 months.The main toxicity was nyelosuppression,gastroin-testinal tract reaction and phlebitis.Conclusion Docetaxel combined w... |
| Keywords: | FOLFOX |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |