| 甲状腺微小癌预后相关因素探讨 |
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| 引用本文： | 董剑达,叶兵,朱少俊,张银龙,郑志强.甲状腺微小癌预后相关因素探讨[J].中国基层医药,2011,18(12):1596-1598. |
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| 作者姓名： | 董剑达 叶兵 朱少俊 张银龙 郑志强 |
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| 作者单位： | 温州医学院附属第二医院普外科,浙江省温州,325014 |
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| 摘 要： | 目的 探讨影响甲状腺微小癌预后的相关因素.方法 收集203例甲状腺微小癌患者的临床资料,回顾性分析临床、病理及治疗等因素与预后的关系.结果 10年疾病相关生存率和无复发生存率分别为100.0%和91.4%.单因素分析显示,癌灶个数〉1个、颈部淋巴结转移和术后放射性碘治疗与肿瘤复发相关.多因素分析显示,颈部淋巴结转移是影响肿瘤复发的独立性危险因素,使肿瘤局部复发率增加2.5倍.结论 甲状腺微小癌的发生率逐年增加,但总体预后良好.颈部淋巴结转移是影响其预后最重要的因素.
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| 关 键 词： | 甲状腺肿瘤 预后 淋巴转移 |
Investigation on the related prognostic factors of the patients with thyroid microcarrinoma |
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| DONG Jian-da,YE Bing,ZHU Shao-jun,ZHANG Yin-long,ZHENG Zhi-qiang.Investigation on the related prognostic factors of the patients with thyroid microcarrinoma[J].Chinese Journal of Primary Medicine and Pharmacy,2011,18(12):1596-1598. |
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| Authors: | DONG Jian-da YE Bing ZHU Shao-jun ZHANG Yin-long ZHENG Zhi-qiang |
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| Institution: | DONG Jian-da(Department of General Surgery,The Second Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325014,China) YE Bing(Department of General Surgery,The Second Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325014,China) ZHU Shao-jun(Department of General Surgery,The Second Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325014,China) ZHANG Yin-long(Department of General Surgery,The Second Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325014,China) ZHENG Zhi-qiang(Department of General Surgery,The Second Hospital Affiliated to Wenzhou Medical College,Wenzhou,Zhejiang 325014,China) |
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| Abstract: | Objective To explore the related prognostic factors of the patients with thyroid microcarcinoma.Methods Clinical data,including clinical,pathologic,and therapeutic factor of 203 patients with thyroid microcarcinoma admitted were analyzed retrospectively.Results The cause specific survival and locoregional failure free survival rates at 10 years were 100.0% and 91.4% , respectively.Univariate analysis showed that multifocality, cervical lymph node metastasis and radioiodine treatment was associated with prognosis.Multivariate analysis revealed that cervical lymph node metastasis was the only independent prognostic factor for locoregional failure free survival.The risk of locoregional recurrence increased 2.5 folds when lymph nodes metastasis occurred at presentation.Conclusion The ratio of thyroid microcarcinoma to thyroid carcinoma increased yearly and the overall survival rate of thyroid microcarcinoma was excellent.Of all the prognostic factors,lymph node metastasis was the most important one related to survival. |
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| Keywords: | Thyroid neoplasms Prognosis Lymphatic metastasis |
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