小剂量芬太尼复合罗哌卡因用于蛛网膜下腔阻滞麻醉的效果

目的探讨小剂量芬太尼复合罗哌卡因用于蛛网膜下腔阻滞麻醉的安全性和有效性。方法选择ASAⅠ-Ⅱ级的产妇80例，按加入芬太尼的不同剂量随机分为F0组（无芬太尼）、R组（芬太尼5μg）、F10组（芬太尼10帖）和F15组（芬太尼15船），于L2-3间隙行腰硬联合穿刺，在蛛网膜下腔以0．1ml/s的速度分别给药（1％罗哌卡因1ml＋10％葡萄糖1ml＋芬太尼不同剂量＋0．9％氯化钠注射液不同剂量），观察各组产妇的心率、血压、感觉及运动阻滞起效和恢复时间、最大感觉阻滞时间和最高阻滞平面、最强运动阻滞时间和阻滞程度、术中和术后不良反应发生率，新生儿1min和5min Apgar评分。结果F10组和F15组感觉阻滞恢复时间明显长于F5组和F0组。结论芬太尼复合罗哌卡因在感觉起效时间、阻滞时间、阻滞平面方面与剂量无关，剂量仅与感觉恢复时间有关。

The application of low dose fentanyl combined ropivacaine on subarachnoid block for cesarean section

Objective To explore the clinical efficacy and safety of low dose fentanyl combined to ropivacaine in subarachnoid block for cesarean section.Methods Eighty patients with ASA physical status Ⅰ and Ⅱscheduled to undergo cesarean section for delivery were randomly allocated to receiving spinally mixture none fentanyl ( group R),5 μg fentanyl ( group F5 ), 10 μg fentanyl ( group F10 ), and 15μg fentanyl ( group F15 ), combined with 1%ropivacaine 1 ml and 10% glucose 1 ml respectively,after combined spinal-epidural anesthesia puncture was applied at the L2～3 interspace.Heart rate, blood pressure, the onset and recovery time of the sensory and motor block,time to the highest level and the highest level of sensory block, time to the maximal extent and the maximal extent of the motor block were recorded at regular intervals.The adverse effects were sought during and after surgery.Neonatal outcome was assessed using Apgar score.Results The recovery of sensory block was prolonged significantly in group F10 and group F15 than in group R and group F5.Conclusion Ropivacaine with 10μg fentanyl is safe and effective in subarachnoid block for cesarean section.