柴牡醒脑汤加减对脑卒中认知功能障碍患者脑血流动力学和认知功能恢复的影响

目的 探讨柴牡醒脑汤加减对脑卒中认知功能障碍患者脑血流动力学和认知功能恢复的影响。方法 选取2019年12月至2020年12月我院收治的212例脑卒中认知功能障碍患者作为研究对象,通过抛硬币法将其分为对照组（106例,常规治疗+认知功能康复训练）和研究组（106例,常规治疗+认知功能康复训练+柴牡醒脑汤加减）。比较两组患者治疗前及治疗6、12周后的脑血流动力学指标、认知功能状态。结果 治疗6、12周后,两组的Vm、Vs均升高,RI、PI均降低,且研究组优于对照组,差异具有统计学意义（P<0.05）。治疗6、12周后,两组的NCES、MoCA评分均升高,且研究组高于对照组,差异具有统计学意义（P<0.05）。结论 给予脑卒中认知功能障碍患者柴牡醒脑汤加减治疗,可促进脑血流量的恢复,进而显著改善患者的认知功能,值得临床推广和应用。

Effect of modified Chaimu Xingnao decoction on cerebral hemodynamic and cognitive function recovery in patients with cognitive impairment after stroke

Objective To investigate the effect of modified Chaimu Xingnao decoction on cerebral hemodynamic and cognitive function recovery in patients with cognitive impairment after stroke.Methods A total of 212 patients with cognitive impairment after stroke treated in our hospital from December 2019 to December 2020 were selected as the research objects and divided into control group(106 cases,conventional treatment+cognitive function rehabilitation training)and study group(106 cases,conventional treatment+cognitive function rehabilitation training+modified Chaimu Xingnao decoction)by coin tossing method.The cerebral hemodynamic indexes and cognitive function status of the two groups of patients before treatment,and after 6 and 12 weeks of treatment were compared.Results After 6 and 12 weeks of treatment,Vm and Vs of the two groups increased,RI and PI decreased,those in the study group were better than the control group,and the differences were statistically significant(P<0.05).After 6 and 12 weeks of treatment,the NCES and MoCA scores of the two groups increased,those in the study group were higher than the control group,and the differences were statistically significant(P<0.05).Conclusion Modified Chaimu Xingnao decoction for stroke patients with cognitive dysfunction can promote the recovery of cerebral blood flow,and significantly improve the cognitive function of patients,which is worthy of clinical promotion and application.