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术中持续输注右美托咪定对甲状腺肿瘤患者应激反应及术后出血的影响
引用本文:黄朝胜,郭翠. 术中持续输注右美托咪定对甲状腺肿瘤患者应激反应及术后出血的影响[J]. 临床医学研究与实践, 2022, 7(8): 89-92
作者姓名:黄朝胜  郭翠
作者单位:安康市人民医院麻醉科,陕西 安康,725000
摘    要:
目的 探讨术中持续输注右美托咪定对甲状腺肿瘤患者应激反应及术后出血的影响.方法 选择2019年10月至2020年10月我院甲状腺科收治的94例甲状腺肿瘤患者为研究对象,根据随机数字表法将其分为研究组和对照组,各47例.研究组从手术开始至结束持续泵注0.5μg/(kg·h)右美托咪定,对照组从手术开始至结束持续泵注等量生...

关 键 词:右美托咪定  术中持续输注  甲状腺肿瘤  应激反应  呛咳反应  术后出血

Effects of intraoperative continuous infusion of dexmedetomidine on stress response and postoperative bleeding in patients with thyroid tumors
HUANG Chaosheng,GUO Cui. Effects of intraoperative continuous infusion of dexmedetomidine on stress response and postoperative bleeding in patients with thyroid tumors[J]. Clinical Research and Practice, 2022, 7(8): 89-92
Authors:HUANG Chaosheng  GUO Cui
Affiliation:(Anesthesiology Department,Ankang People's Hospital,Ankang 725000,China)
Abstract:
Objective To investigate the effects of intraoperative continuous infusion of dexmedetomidine on stress response and postoperative bleeding in patients with thyroid tumors.Methods Ninety-four patients with thyroid tumors treated in the thyroid department of our hospital from October 2019 to October 2020 were selected as the research objects and divided into study group and control group according to the random number table method,with 47 cases in each group.The study group was continuously pumped with 0.5μg/(kg·h)dexmedetomidine from the beginning to the end of the operation,and the control group was continuously pumped with the same amount of normal saline from the beginning to the end of the operation.The mean arterial pressure(MAP),heart rate(HR),pulse oxygen saturation(SpO2),epinephrine(E)and adrenocortical hormone levels were compared between the two groups at different time points.The incidence of choking reaction during tracheal extubation,recovery time and postoperative bleeding were compared between the two groups.Results Before anesthesia,there were no significant differences in the MAP,HR,SpO2,E and adrenocortical hormone levels between the two groups(P>0.05);the MAP,HR,E and adrenocortical hormone levels in the study group at 1 min after anesthesia intubation and at 1 min after removal of anesthesia tube were significantly lower than those in the control group,while SpO2 was higher than that in the control group(P<0.05).The total incidence of choking reaction during tracheal extubation in the study group was 10.64%,which was significantly lower than 27.66%in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in postoperative recovery time of spontaneous breathing,tracheal extubation time and hospital stay between the two groups(P>0.05);the wound healing time of the study group was shorter than that of the control group,the amount of bleeding at 24 and 48 h after operation was less than that of the control group,and the differences was statistically significant(P<0.05).Conclusion Intraoperative continuous infusion of dexmedetomidine can effectively inhibit the body's stress response,reduce choking reaction and postoperative bleeding,which is of positive significance to ensure the smooth implementation of thyroid tumor surgery and anesthesia recovery,with high application value.
Keywords:dexmedetomidine  intraoperative continuous infusion  thyroid tumor  stress response  choking reaction  postoperative bleeding
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