布地奈德联合硫酸特布他林雾化吸入治疗小儿呼吸道感染后咳嗽的临床效果

目的 评价布地奈德联合硫酸特布他林雾化吸入治疗小儿呼吸道感染后咳嗽的临床效果.方法 回顾性选取2018年1月至2020年1月本院收治的88例小儿呼吸道感染后咳嗽为研究对象,依据治疗方法的不同将其分为对照组和观察组,每组44例.对照组患儿采取硫酸特布他林雾化吸入治疗,观察组患儿采取布地奈德联合硫酸特布他林雾化吸入治疗.比...

Clinical effect of atomization inhalation of budesonide combined with terbutaline sulfate in the treatment of cough after respiratory tract infection in children

Objective To evaluate the clinical effect of atomization inhalation of budesonide combined with terbutaline sulfate in the treatment of cough after respiratory tract infection in children.Methods A total of 88 children with cough after respiratory tract infection treated in our hospital from January 2018 to January 2020 were retrospectively selected as the research objects,and the children were divided into control group and observation group according to different treatment methods,with 44 cases in each group.The control group was treated with terbutaline sulfate atomization inhalation,and the observation group was treated with atomization inhalation of budesonide combined with terbutaline sulfate.The levels of serum interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α),clinical efficacy,disappearance time of symptoms/signs and occurrence of adverse reactions were compared between the two groups.Results Before treatment,there were no significant differences in the levels of serum IL-6 and TNF-αbetween the two groups(P>0.05);after treatment,the levels of serum IL-6 and TNF-αdecreased in both groups,those in the observation group were significantly lower than the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment of the observation group was 97.73%,which was significantly higher than 77.27%of the control group,and the difference was statistically significant(P<0.05).The disappearance time of high fever,shortness of breath,wet rale and cough in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was 4.55%,which was significantly lower than 18.18%in the control group,and the difference was statistically significant(P<0.05).Conclusion The atomization inhalation of budesonide combined with terbutaline sulfate has a remarkable effect in the treatment of cough after respiratory tract infection in children.It can significantly reduce inflammatory reaction,and effectively alleviate clinical symptoms/signs,with high safety.