| 骨关节炎生物标记物COMP的研究进展 |
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| 引用本文： | 朱台航,蔡春元,张雷. 骨关节炎生物标记物COMP的研究进展[J]. 中国骨伤, 2010, 23(12): 959-961. DOI: 10.3969/j.issn.1003-0034.2010.12.026 |
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| 作者姓名： | 朱台航 蔡春元 张雷 |
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| 作者单位： | 温州医学院附属第三医院骨科,浙江,温州,325200 |
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| 摘 要： | 血清寡聚基质蛋白(COMP)是骨性关节炎的一个潜在的生物标记物,迄今为止COMP是最先研究的且一直被认为能较好反映骨性关节炎发生、进展及预后情况的生物学指标。本文简要阐述其多重用途,并总结先前的研究报道以促进对COMP的进一步研究。
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| 关 键 词： | 骨关节炎 生物学标记 血清寡聚基质蛋白 综述文献 |
| 收稿时间： | 2010-08-15 |
Research progress of biomarker COMP in osteoarthritis |
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| ZHU Tai-hang,CAI Chun-yuan and ZHANG Lei. Research progress of biomarker COMP in osteoarthritis[J]. China journal of orthopaedics and traumatology, 2010, 23(12): 959-961. DOI: 10.3969/j.issn.1003-0034.2010.12.026 |
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| Authors: | ZHU Tai-hang CAI Chun-yuan ZHANG Lei |
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| Affiliation: | Department of Orthopaedics and Trauma Surgery, the Third Affiliated Hospital of Wenzhou Medical College, Wenzhou 325200, Zhejiang, China;Department of Orthopaedics and Trauma Surgery, the Third Affiliated Hospital of Wenzhou Medical College, Wenzhou 325200, Zhejiang, China;Department of Orthopaedics and Trauma Surgery, the Third Affiliated Hospital of Wenzhou Medical College, Wenzhou 325200, Zhejiang, China |
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| Abstract: | Cartilage oligomeric matrix protein(COMP) is a potential biomarker for joint destruction associated with osteoarthritis,which is first and best investigated biomarkers to reflect osteoarthritis occurs,progress and the prognosis. In this article,multiple uses and related reports of COMP are summarized briefly to promote further investigation of COMP. |
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| Keywords: | Osteoarthritis Biological markers Cartilage oligomeric matrix protein Review literature |
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