血液灌流联合日间高容量血液滤过在重症急性胰腺炎治疗中的作用

目的 探讨血液灌流联合日间高容量血液滤过在重症急性胰腺炎中的治疗价值.方法 回顾性分析25例行血液灌流联合日间高容量血液滤过治疗的重症急性胰腺炎患者(观察组)的临床资料,并与同期未行血液净化治疗的30例重症急性胰腺炎患者(对照组)进行对比.结果 观察组血液生化指标治疗后较治疗前明显好转.观察组较对照组住院时间缩短[(21.6±12.3)d与(30.8±15.6)d]、治愈率高(72％与40％)、病死率低(16％与30％)(均P＜0.05),但治疗费用相当.结论 对重症急性胰腺炎患者,在常规治疗基础上尽早行血液灌流联合日间高容量血液滤过治疗,可提高抢救成功率,缩短住院时间,疗效确切.

The effect of hemoperfusion combined with daytime high capacity hemofiltration in the treatment of severe acute pancreatitis

Objective To explore the therapeutic value of hemoperfusion combined with daytime high capacity hemofihration in the treatment of severe acute pancreatitis. Methods The clinical data of 25 patients with severe acute pancreatitis treated by hemoperfusion combined with daytime high capacity hemofiltration （the observation group） were retrospectively analyzed, and compared with 30 severe acute pancreatitis patients without blood purification treatment（ the control group ）. Results After the treatment, the biochemical indicator of the observation group was improved obviously compared with pre-treatment. Of the observation group, the hospital staying time was shorter [ （ 21.6 ± 12.3 ） d vs （ 30.8 ± 15.6 ） d ], and the cure rate was higher （ 72% vs 40% ）, and the death rate was lower （16% vs 30% ） ,compared with the control group（ all P 〈 0.05 ）, but the treatment costs had no difference between the two groups. Conclusion Patients with severe acute pancreatitis on the basis of conventional treatment should con- duct as early as possible hemoperfusion combined with daytime high capacity hemofihration, and it could improve the success rate of the rescue and shorthen the length of hospital stay, and its curative effect was accurate.