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| 食管癌患者手术前后血浆D-二聚体动态变化的临床意义 | |
| 引用本文： | 黄明伟,唐志苗,王健,张德意,杜忠明,付冠华,夏银献,周志有.食管癌患者手术前后血浆D-二聚体动态变化的临床意义[J].中国基层医药,2012,19(13):1929-1930. |
| 作者姓名： | 黄明伟 唐志苗 王健 张德意 杜忠明 付冠华 夏银献 周志有 |
| 作者单位： | 1. 金华市中心医院急诊医学科, 浙江省金华,321000 2. 金华市中心医院心胸外科, 浙江省金华,321000 3. 金华市中心医院检验医学科, 浙江省金华,321000 |
| 基金项目： | 浙江省金华市科学技术研究计划项目 |
| 摘 要： | 目的 探讨食管癌患者手术前后血浆D-二聚体动态变化与其生存率的关系.方法 对照组30例、食管癌组160例(其中手术例数112例),用金标法测定血浆D-二聚体水平.结果 血浆D-二聚体水平与食管癌患者TNM分期、淋巴结转移情况及肿瘤大小相关.与术前比较,术后2年血浆D-二聚体明显升高(t =7.35,P＜0.05).结论 血浆D-二聚体手术前后的动态变化与食管癌患者近期生存率相关. |
| 关 键 词： | 食管肿瘤 D-二聚体 生存率 |
The clinical significance of dynamic changes of serum D-dimers in esophageal carcinoma pre-and post-operation |
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| HUANG Ming-wei , TANG Zhi-miao , WANG Jian , ZHANG De-yi , DU Zhong-ming , FU Guan-hua , XIA Yin-xian , ZHOU Zhi-you.The clinical significance of dynamic changes of serum D-dimers in esophageal carcinoma pre-and post-operation[J].Chinese Journal of Primary Medicine and Pharmacy,2012,19(13):1929-1930. | |
| Authors: | HUANG Ming-wei TANG Zhi-miao WANG Jian ZHANG De-yi DU Zhong-ming FU Guan-hua XIA Yin-xian ZHOU Zhi-you |
| Institution: | . Department of Emergency, the Central Hospital of Jinhua, Jinhua, Zhefiang 321000, China |
| Abstract: | Objective To investigate the relationship between dynamic changes of plasma D-dimer and sur- vival rate of the esophageal carcinoma patients pre-and post-operation. Methods 30 cases of normal conirol group, 160 cases of esophageal cancer group（ including operation cases n = 112） ,with the gold standard method foi the deter- mination of plasma D-dimer. Results There was a link between the level of D-dimer,TNM staging, lymph node me- tastasis and tumor size in esophageal carcinoma patients. Compared with the preoperation, the plasma D-dilner is sig- nificantly elevated 2 years later（ t = 7.35,P 〉 0.05 ）. Conclusion Before or after the operation, dynamic changes of plasma D-dimer had a relationship with short-term survival rate. |
| Keywords: | Esophageal neoplasms D-dimer Survival rate |
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