Relationship between parameters of lipid peroxidation during obstructive jaundice and after bile flow restoration |
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| Authors: | L B Dudnik A N Tsupko M A Shupik G G Akhaladze E I Galperin L V Platonova E A Pantaz A V Alessenko |
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| Institution: | (1) E. M. Emanuel’ Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia;(2) I. M. Sechenov Moscow Medical Academy, Moscow, Russia |
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| Abstract: | Restoration of bile flow after 9-day cholestasis in rat liver normalized the content of lipid peroxidation products. The removal
of the cholestatic factor after 12-day cholestasis was not followed by recovery of these parameters. We showed that measurement
of serum concentration of lipid peroxidation products in patients with cholelithiasis during the preoperative period holds
promise for selection of the optimum time for surgical treatment and prediction of the risk of postoperative complications.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 1, pp. 39–42, January, 2008 |
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| Keywords: | lipid peroxidation cholelithiasis common bile duct ligation liver blood serum |
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