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蔡氏扶正消瘕汤对胃癌细胞体外生长的影响
引用本文:尹丽慧 郎玮 叶人 吴建波 蔡慎初. 蔡氏扶正消瘕汤对胃癌细胞体外生长的影响[J]. 温州医学院学报, 2006, 36(1): 39-41
作者姓名:尹丽慧 郎玮 叶人 吴建波 蔡慎初
作者单位:[1]温州医学院第一附属医院医科所,浙江温州325000 [2]温州医学院第一附属医院中医科,浙江温州325000
基金项目:浙江省中医药管理局课题基金资助项目(2000C85).
摘    要:
目的:探讨蔡氏扶正消癌汤对人低分化胃癌细胞BGC-823体外生长的影响。方法:采用四甲基偶氮唑蓝(MTT)还原法检测蔡氏扶正消瘢汤对BGC-823生长的影响,并观察蔡氏扶正消瘦汤对BGC-823细胞形态的影响。结果:蔡氏扶正消瘦汤生药能抑制BGC-823的生长。在实验浓度范围内,随着剂量的增加,抑制作用更加明显;同一剂量下,72h内药物作用时间越长,抑制作用越明显。结论:蔡氏扶正消瘦汤能够抑制低分化胃癌细胞BGC-823的生长。

关 键 词:中药复方 胃癌细胞 增殖
文章编号:1000-2138(2006)01-0039-03
收稿时间:2005-06-13
修稿时间:2005-06-13

Effect of Cai''''s-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro
YIN Li-hui, LANG wei, YE Ren,et al.. Effect of Cai''''s-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro[J]. Journal of Wenzhou Medical College, 2006, 36(1): 39-41
Authors:YIN Li-hui   LANG wei   YE Ren  et al.
Affiliation:Medical Science Institute of the Firt Affiliated ttospital of Wenzhou Nedical College. Wenzhou 325011
Abstract:
Objective: To study the effect of Cai's-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro. Methods: Growth of Cai's-fu-zheng-xiao-zheng-tang on BGC-823 cells was measured with MTT colorimetric assay after treated by various concentrations of Cai's-fu-zheng-xiao-zheng-tang. Morphological changes of BGC-823 cells were observed under light microscope. Results: Cai's-fu-zheng-xiao-zheng-tang inhibited the growth of BGC-823 cells in dose-dependent manner. From 0h to 72h, Cai's-fu-zheng-xiao-zheng-tang at the same concentration inhibited the growth of BGC-823 cells in time-dependent manner. Conclusion: Cai' s-fu-zheng-xiao-zheng-tang can inhibit growth of BGC-823 cells.
Keywords:herbal medicinal mixture   human gastric carcinoma cell   proliferation
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