磁共振灌注成像在小肝癌诊断的价值初探

目的评价MR灌注成像技术对原发性小肝细胞癌（SHCC）的诊断价值。方法手术病理证实SHCC13例共16个小肝癌病灶术前在常规磁共振平扫后采用2D SPGR序列进行T1WIMR灌注成像检查,比较病灶区及正常肝实质时间信号强度（time-intensity curve,TIC）及相关函数图变化。结果小肝癌组峰值时间（timetopeak,TTP）（26.17±6.2）s,正常对照级肝实质TTP（54.92±9.26）s,P＆lt;0.01。结合MRI平扫,MR灌注成像技术对原发性小肝细胞癌诊断符合率为87.5%。结论MR灌注成像技术可以提供比传统图像准确的肿瘤血供信息,对小肝癌的诊断及鉴别提供了一种新的较有效方法。

Initial Evaluation with Perfusion Weighted MR Imaging on Diagnosis of SHCC

Objective The current study was designed to observe the diagnostic value of magnetic resonance perfusion wighted imaging（MR PWI） on small hepatic cell cancer（SHCC）.Methods The MRI and MR PWI of 16 lesions of SHCC was retrospectively analyzed in 13 patients.The imaging sequences included T1-weighted imaging and T2-weighted imaging, additionally MR PWI and T1-weighted imaging with injection of the contrast agent of Gd-DTPA was performed in all cases. Results Sixteen lesions were found in lest and right lobe of liver in 13cases.The lesions of SHCC displayed homogenous long T2and logn T1 abnormal signal. The time to peak of SHCC was（26.17± 6.24）s,and （54.92 ± 9.26）s of TTP was presented in control group.Conclusion MR PWI can effectively reveal blood supply information of hepatic cancer and could have some profits in diagnosis of SHCC.