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小鼠部分肝切除术的现状与应用
引用本文:李一,胡建军,韩伟,俞雁. 小鼠部分肝切除术的现状与应用[J]. 世界华人消化杂志, 2011, 0(3): 275-280
作者姓名:李一  胡建军  韩伟  俞雁
作者单位:上海交通大学农业与生物学院兽医生物技术上海市重点实验室;上海交通大学医学院附属上海市第六人民医院感染科;上海交通大学药学院再生医学实验室;
摘    要:
部分肝切除术创建于20世纪30年代,他为哺乳动物的肝再生和肝疾病等研究提供了重要的实验工具,现有的手术方法主要以大鼠和小鼠为对象.小鼠的部分肝切除手术与大鼠的手术方法有较大的相似性,但因其体质差异不能完全复制大鼠的手术方法.本文结合文献报道和实践操作的经验,除了对部分肝切除术的原理和主要方法进行介绍外,也对小鼠部分肝切...

关 键 词:肝部分切除术  肝再生  小鼠

Partial hepatectomy in mice: current status of research and implications for clinical practice
Yi Li,Yan Yu,Shanghai Municipality Key Laboratory for Veterinary Biotechnology,School of Agriculture , Biology,Shanghai Jiao Tong University,Shanghai ,China Jian-Jun Hu. Partial hepatectomy in mice: current status of research and implications for clinical practice[J]. World Chinese Journal of Digestology, 2011, 0(3): 275-280
Authors:Yi Li  Yan Yu  Shanghai Municipality Key Laboratory for Veterinary Biotechnology  School of Agriculture    Biology  Shanghai Jiao Tong University  Shanghai   China Jian-Jun Hu
Affiliation:Yi Li,Yan Yu,Shanghai Municipality Key Laboratory for Veterinary Biotechnology,School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai 200240,China Jian-Jun Hu,Department of Infectious Diseases,Shanghai Sixth People's Hospital,Shanghai 200233,China Wei Han,Laboratory for Regenerative Medicine,School of Pharmacy,China
Abstract:
The classic model of partial hepatectomy was first established in the 1930s and played a key role in the research of liver regeneration and liver disease in mammals. Rats and mice are the most commonly used animals for research, but surgery is usually performed in rats. Considering many differences between rats and mice, this paper aims to summarize the crucial points in the surgical procedure for mice and the principles and methods of partial hepatectomy.
Keywords:Partial Hepatectomy  Liver regeneration  Mouse  
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