| Twist1,MMP-2和MMP-9在结直肠癌组织中的表达及意义 |
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| 引用本文： | 杨振忠,吴正升,法文,李守新,吕永芳. Twist1,MMP-2和MMP-9在结直肠癌组织中的表达及意义[J]. 世界华人消化杂志, 2011, 0(3): 314-317 |
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| 作者姓名： | 杨振忠 吴正升 法文 李守新 吕永芳 |
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| 作者单位： | 新华医疗集团新华医院病理科;安徽医科大学病理学教研室; |
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| 摘 要： | 目的:研究Twist1、MMP-2和MMP-9蛋白在结直肠癌组织中的表达及其相互关系.方法:建立组织微阵列平台,应用免疫组织化学方法检测92例结直肠癌组织Twist1、MMP-2和MMP-9蛋白的表达情况.结果:结直肠癌中Twist1的表达率为64.1%,MMP-2和MMP-9阳性率分别为66.3%和67.4%;Twi...
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| 关 键 词： | 结直肠癌 Twist1 MMP-2 MMP-9 免疫组织化学 |
Expression of Twist1, MMP-2 and MMP-9 in colorectal cancer |
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| Zhen-Zhong Yang,Wen Fa,Shou-Xin Li,Yong-Fang Lv. Expression of Twist1, MMP-2 and MMP-9 in colorectal cancer[J]. World Chinese Journal of Digestology, 2011, 0(3): 314-317 |
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| Authors: | Zhen-Zhong Yang Wen Fa Shou-Xin Li Yong-Fang Lv |
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| Affiliation: | Zhen-Zhong Yang,Wen Fa,Shou-Xin Li,Yong-Fang Lv,Department of Pathology,Xinhua Hospital,Huainan Xinhua Medical Group,Huainan 232052,Anhui Province,China Zheng-Sheng Wu,Anhui Medical University,Hefei 230032,China |
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| Abstract: | AIM: To investigate the clinical significance of the expression of Twist1, MMP-2 and MMP-9 proteins in colorectal cancer. METHODS: The expression of Twist1, MMP-2 and MMP-9 proteins was examined on tissue chips containing 92 colorectal cancer samples by immunohistochemistry. RESULTS: The positive rates of Twist1, MMP-2 and MMP-9 protein expression in colorectal cancer were 64.1%, 66.3% and 67.4%, respectively. High expression of Twist1 was positively correlated with lymph node metastasis and TNM stage (both... |
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| Keywords: | Colorectal cancer Twist1 MMP-2 MMP-9 Immunohistochemistry |
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