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乙型肝炎肝硬化的抗病毒治疗
引用本文:朱传武,王海燕,方焕.乙型肝炎肝硬化的抗病毒治疗[J].世界华人消化杂志,2011(15):1591-1597.
作者姓名:朱传武  王海燕  方焕
作者单位:苏州市第五人民医院肝病科;
摘    要:乙型肝炎肝硬化患者接受抗病毒治疗可以获得生化学缓解和组织学改善,部分患者甚至获得了肝硬化的完全逆转,显著降低了肝脏失代偿、肝癌以及肝病相关死亡的发生.干扰素可用于代偿期肝硬化有限疗程的抗病毒治疗,核苷(酸)类似物可用于代偿期和失代偿期肝硬化的长期抗病毒治疗.治疗期间需密切监测生化学和病毒学变化,及早发现病毒学突破,阻止...

关 键 词:肝硬化  乙型肝炎病毒  抗病毒治疗

Antiviral therapy in patients with hepatitis B virus-related cirrhosis
Chuan-Wu Zhu,Hai-Yan Wang,Huan Fang.Antiviral therapy in patients with hepatitis B virus-related cirrhosis[J].World Chinese Journal of Digestology,2011(15):1591-1597.
Authors:Chuan-Wu Zhu  Hai-Yan Wang  Huan Fang
Institution:Chuan-Wu Zhu,Hai-Yan Wang,Huan Fang,Department of Hepatology,the Fifth People's Hospital of Suzhou,Su-zhou 215007,Jiangsu Province,China
Abstract:Antiviral therapy can lead to biochemical remission,histological improvement,and even complete reversibility of liver cirrhosis in patients with hepatitis B virus-related cirrhosis,thereby significantly reducing the incidence of hepatic decompensation,hepatocellular carcinoma and liver disease-related death.Interferon alpha is not contraindicated in compensated cirrhosis and can be used in finite treatment for 6 or 12 months.Long-term treatment with nucleoside/nucleotide analogues is recommended for both co...
Keywords:Liver cirrhosis  Hepatitis B virus  Antiviral therapy  
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