血清载脂蛋白水平在HBV慢性肝病肝损伤程度判断中的作用 |
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引用本文: | 邢欣悦,刘梅,郑素军,张莹,武聚山,俞豪,李长勇,白丽,刘霜,段钟平. 血清载脂蛋白水平在HBV慢性肝病肝损伤程度判断中的作用[J]. 世界华人消化杂志, 2011, 0(3): 295-300 |
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作者姓名: | 邢欣悦 刘梅 郑素军 张莹 武聚山 俞豪 李长勇 白丽 刘霜 段钟平 |
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作者单位: | 首都医科大学附属北京佑安医院人工肝中心;首都医科大学基础医学院细胞生物学系; |
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基金项目: | “艾滋病和病毒性肝炎等重大传染病防治”科技重大专项课题基金资助项目,No.2008ZX10002-005-3; 国家自然科学基金资助项目,No.30800979; 北京自然科学基金资助项目,No.7102085; 北京市科技新星资助项目,No.2007B055; 首都医科大学基础-临床科研合作基金,No.2007JL02;2010JL02; 北京市教育委员会科技发展计划项目基金资助项目,No.KM201010025024~~ |
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摘 要: | 目的:研究HBV慢性肝病中的血清载脂蛋白水平的变化与肝损伤严重程度的关系.方法:113例HBV相关的慢性肝病患者,其中慢性乙型肝炎33例,肝硬化46例,重型肝炎肝衰竭34例,肝衰竭又分为良好预后组和不良预后组,检测其入院时空腹血清载脂蛋白ApoA1和ApoB水平,计算患者的MELD和Child-Pugh评分,并分析Ap...
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关 键 词: | 血清载脂蛋白 载脂蛋白A1 载脂蛋白B 乙型肝炎病毒 慢性肝病 肝损伤 |
Significance of serum apolipoprotein levels in assessing the degree of liver injury in patients with HBVrelated chronic liver disease |
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Abstract: | AIM: To observe the changes in serum apolipoprotein levels in patients with HBV-related chronic liver disease and to assess the relationship between serum apolipoprotein levels and the degree of liver injury in these patients. METHODS: A total of 113 patients with HBVrelated chronic liver disease were involved in the study, including 33 patients with chronic hepatitis B, 46 patients with liver cirrhosis and 34 patients with liver failure. Patients with liver failure were further subdivided into good prognos... |
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Keywords: | Serum apolipoprotein Apolipoprotein A1 Apolipoprotein B Hepatitis B virus Chronic liver disease Liver injury |
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